Alessandro Canella
Biochemistry, Genetics and Molecular Biology · The Ohio State University
Publications
124
Citations
1,660
Est. group size
~10
Recurring co-author estimate
Active years
52
Publishing since 1975
Alessandro Canella's research focuses on brain cancers (especially glioma and glioblastoma) and leukemia, studying how tumor cells interact with the immune system and how specific genes and proteins drive cancer growth, treatment resistance, and stem-cell-like properties in tumors. Work spans molecular mechanisms (such as LEDGF/p75, CD74, and Hedgehog signaling) to potential immune-based and cell-engineering therapies.
Publication output was low and irregular from 2017-2020, then increased substantially with a peak in 2023, followed by a decline in 2024-2026.
Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026
- The Dickkopf-1 (DKK1) Dichotomy in Oncology: New Insights on Tumor Progression and Immune Regulation
International Journal of Molecular Sciences · 2026
- Identification of an immunomodulatory lncRNA signature associated with immune cell reprogramming in high-grade glioma
Cancer Gene Therapy · 2025
- TMIC-50. Targeting MHCII invariant chain transmembrane protein CD74 confers a survival advantage in a preclinical model of glioma malignant progression
Neuro-Oncology · 2025
- 895 Immunomodulatory role of CD74 in low-grade glioma bone marrow-derived myeloid cells
Regular and Young Investigator Award Abstracts · 2024
- PB1704: LEDGF/P75 ASSOCIATED WITH CHEMORESISTANCE IN MIXED-LINEAGE LEUKEMIA
HemaSphere · 2023
- Therapeutic utility of engineered myeloid cells in the tumor microenvironment
Cancer Gene Therapy · 2023
- Unlike its Paralog LEDGF/p75, HRP-2 Is Dispensable for MLL-R Leukemogenesis but Important for Leukemic Cell Survival
Cells · 2021
- LEDGF/p75-mediated chemoresistance of mixed-lineage leukemia involves cell survival pathways and super enhancer activators
Cancer Gene Therapy · 2021
- PF219 THE LEDGF/P75 HOMOLOG HRP2 IS NOT IMPORTANT FOR THE INITIATION OF MLL‐REARRANGED LEUKEMIA
HemaSphere · 2019
- Ruthenium complexes containing mPTA and thiopurines bis(8-thiotheophylline)-(CH <sub>2</sub> ) <sub>n</sub> (n = 1 – 3; mPTA = N-methyl-1,3,5-triaza-7-phosphaadamantane)
Journal of Coordination Chemistry · 2017
- Abstract 2519: A novel role for brachyury as a key regulator of sonic hedgehog signaling (Shh) and maintenance of stemness in gliomas
Cancer Research · 2016
- CSIG-28. NOVEL FUNCTION OF BRACHYURY AS A POTENT REGULATOR OF HEDGEHOG SIGNALING AND STEMNESS IN GLIOMA
Neuro-Oncology · 2016
- RBIO-06. CROSSTALK OF ErbB2 WITH LEF1 REGULATES JAGGED1-MEDIATED RADIORESISTANCE IN GLIOBLASTOMA
Neuro-Oncology · 2016
- Neuro-Oncology×8
- Regular and Young Investigator Award Abstracts×4
- Cancer Gene Therapy×3
- Molecular Therapy Oncology×3
- bioRxiv (Cold Spring Harbor Laboratory)×3
- Mayu Fukuda
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- Prabakaran Nagarajan
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- Jie Zhang
Medicine · Indiana University
- Huaqun Zhang
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- Naduparambil K. Jacob
Biochemistry, Genetics and Molecular Biology · The Ohio State University
This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.
Last updated Jul 19, 2026.
Claim or correct this profile