Huaqun Zhang

Huaqun Zhang's research focuses on the structural biology of protein quality control and RNA-based gene silencing pathways. Work includes studying how molecular chaperones (like Hsp70) and the enzyme CHIP tag misfolded proteins for degradation, and how small RNA molecules such as microRNAs and siRNAs are processed and used by Argonaute proteins to silence genes. This combines crystal structures, biochemistry, and biophysics to understand molecular mechanisms relevant to cellular stress responses and RNA-based therapeutics like antisense oligonucleotides.

Publication output has been variable but generally steady over the past decade, with a notable spike of multiple outputs expected in 2026, suggesting an active and possibly growing research pipeline.

Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026