Zihai Li

Zihai Li's research focuses on tumor immunology and cancer immunotherapy, examining how immune cells like T cells and NK cells interact with tumors and how cellular stress pathways (such as protein misfolding and mitochondrial stress) affect immune cell function. The work spans basic mechanisms of immune evasion and exhaustion as well as translational efforts including CAR-T cell therapies, checkpoint blockade combinations, and clinical trials for cancers like glioblastoma, melanoma, and lung cancer.

Publication output has grown substantially over the past decade, rising from about 20 papers per year in 2017-2020 to a peak of 87 in 2023 and remaining high through 2025.

Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026