Zhuyun Bian

Medicine · Purdue University West Lafayette

Mid career · publishing since 2015Rising activity

Fungal Infections and Studies Fungal and yeast genetics research Plant Pathogens and Fungal Diseases Yeasts and Rust Fungi Studies Plant-Microbe Interactions and Immunity

Publications

Citations

323

Est. group size

Recurring co-author estimate

Active years

Publishing since 2015

Research summary

AI-generated

Zhuyun Bian studies the biology of Cryptococcus neoformans, a fungus that causes serious infections in humans, with a focus on how it reproduces (through processes like meiosis, unisexual and parasexual reproduction) and how genetic changes in ploidy (chromosome number) contribute to its biology and pathogenicity. Related work also explores drug-resistance mechanisms in fungi and ways to improve antifungal drug effectiveness, such as combining existing drugs with compounds that block resistance pathways.

Fungal pathogen biology (Cryptococcus neoformans)Fungal reproduction and mating-type geneticsGenome evolution and ploidy dynamics in fungiAntifungal drug resistance and drug combination strategiesMolecular genetics of eukaryotic microbes

Publication output has grown over the last decade, rising from occasional single papers per year to a peak of several publications annually in 2024-2026.

Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026

Publication cadence

Publications per year over the last 10 years — averaging 3.2/year recently

Recent publications

Meiosis-specific genes play roles in ploidy reduction in Cryptococcus neoformans titan cells
Proceedings of the National Academy of Sciences · 2026
Meiosis-specific genes play roles in ploidy reduction in Cryptococcus neoformans titan cells
PubMed Central · 2026
Genomic hallmarks of parasexual reproduction in three hybrid groups of the human pathogen Cryptococcus neoformans
bioRxiv (Cold Spring Harbor Laboratory) · 2026
Fungal sexual reproduction and mating-type loci
Current Biology · 2025
Butyrolactol A enhances caspofungin efficacy via flippase inhibition in drug-resistant fungi
Cell · 2025
Essential genes encoded by the mating-type locus of the human fungal pathogen Cryptococcus neoformans
mBio · 2025
Butyrolactol A potentiates caspofungin efficacy against resistant fungi via phospholipid flippase inhibition
bioRxiv (Cold Spring Harbor Laboratory) · 2025
Unisexual reproduction in the global human fungal pathogen Cryptococcus neoformans
bioRxiv (Cold Spring Harbor Laboratory) · 2025
Unisexual reproduction in the global human fungal pathogen Cryptococcus neoformans 
Proceedings of the National Academy of Sciences · 2025
Essential genes encoded by the mating-type locus of the human fungal pathogen Cryptococcus neoformans
bioRxiv (Cold Spring Harbor Laboratory) · 2024

Publishes in

Proceedings of the National Academy of Sciences×4
bioRxiv (Cold Spring Harbor Laboratory)×4
Environmental Microbiology×2
Cellular and Molecular Life Sciences×1
Stress Biology×1

Similar researchers

By research-topic overlap

Stephanie C. Ray
Medicine · The Ohio State University
Chad A. Rappleye
Medicine · The Ohio State University
Jin‐Rong Xu
Biochemistry, Genetics and Molecular Biology · Purdue University West Lafayette
Joo-Yeon Lim
Biochemistry, Genetics and Molecular Biology · Indiana University
Matthew Z. Anderson
Medicine · The Ohio State University

This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.

Last updated Jul 20, 2026.

Claim or correct this profile