Xiangming Gu
Biochemistry, Genetics and Molecular Biology · The Ohio State University
Publications
28
Citations
164
Est. group size
~6
Recurring co-author estimate
Active years
30
Publishing since 1997
Xiangming Gu works on developing and characterizing blood substitutes based on chemically modified (polymerized) hemoglobin, aiming to create products that can carry oxygen like red blood cells. This includes engineering nanoparticle-based and membrane-based carriers, studying how these substitutes affect blood vessels and heart muscle cells, and scaling up manufacturing methods for producing and purifying these materials. The work bridges biochemistry, bioengineering, and physiology to address the need for alternatives to donated blood.
Publication output rose from none in the late 2010s to a peak of four papers in 2022, then settled into a steady pace of about one to two publications per year through 2026.
Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026
- Acellular Hemoglobin Impairs Cardiomyocyte Excitation-Contraction Coupling
ASAIO Journal · 2026
- Microvascular Consequences of Methemoglobin Compared to Reduced Hemoglobin in the Microcirculation
Microcirculation · 2025
- Tangential flow filtration‐facilitated purification of human red blood cell membrane fragments and its preferential use in removing unencapsulated material from resealed red blood cell ghosts compared to centrifugation
Biotechnology Progress · 2024
- ZIF-8 metal organic framework nanoparticle loaded with tense quaternary state polymerized bovine hemoglobin: potential red blood cell substitute with antioxidant properties
Nanoscale · 2023
- Biophysical Analysis and Preclinical Pharmacokinetics–Pharmacodynamics of Tangential Flow Filtration Fractionated Polymerized Human Hemoglobin as a Red Blood Cell Substitute
Biomacromolecules · 2023
- ZIF-8 Metal–Organic Framework Nanoparticles Loaded with Hemoglobin as a Potential Red Blood Cell Substitute
ACS Applied Nano Materials · 2022
- Pilot scale production and characterization of next generation high molecular weight and tense quaternary state polymerized human hemoglobin
Biotechnology and Bioengineering · 2022
- Scalable manufacturing platform for the production of methemoglobin as a non-oxygen carrying control material in studies of cell-free hemoglobin solutions
PLoS ONE · 2022
- Pilot Scale Production of Polymerized Human Hemoglobin
2022
- Tangential flow filtration facilitated fractionation and PEGylation of low and high‐molecular weight polymerized hemoglobins and their biophysical properties
Biotechnology and Bioengineering · 2021
- Comprehensive characterization of tense and relaxed quaternary state glutaraldehyde polymerized bovine hemoglobin as a function of cross‐link density
Biotechnology and Bioengineering · 2020
- Comprehensive Characterization of Tense and Relaxed State Glutaraldehyde Polymerized Bovine Hemoglobin as a Function of Cross-link Density
Authorea · 2020
- Biotechnology and Bioengineering×3
- ACS Sustainable Chemistry & Engineering×1
- ACS Applied Nano Materials×1
- Cellular and Molecular Bioengineering×1
- Nanoscale×1
- Chintan Savla
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- Andre F. Palmer
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- Mohd Asim Khan
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- Quintin O’Boyle
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- Savannah R. Wolfe
Biochemistry, Genetics and Molecular Biology · The Ohio State University
This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.
Last updated Jul 19, 2026.
Claim or correct this profile