William J. Sullivan
Immunology and Microbiology · Indiana University
Publications
190
Citations
6,088
Est. group size
—
Recurring co-author estimate
Active years
57
Publishing since 1969
William J. Sullivan studies Toxoplasma gondii, a single-celled parasite that infects humans and animals and can persist as dormant tissue cysts. His research focuses on how this parasite switches between growth stages, manages DNA damage and repair, and controls its genes through histone (DNA-packaging protein) modifications, with additional work aimed at finding new drugs to treat infection. Some recent projects also extend to other parasites and to cancer biology models.
Publication activity was higher in the late 2010s (around 11-19 papers per year) and has settled to a lower, roughly steady rate of about 5 per year in the last five years.
Generated by claude-opus-4-8 from public bibliographic data · Jul 9, 2026
Current awards run through January 2028 — about 1 year of funding on record from today. Awards are often renewed, so this is what is currently public, not a forecast.
Mechanisms driving reactivated toxoplasmosis in HIV/AIDS co-infection
Translation initiation factors driving persistence of Toxoplasma gondii bradyzoites in neurons
16 earlier awards
- NIH R21AI174860Jan 2023 – Dec 2025 · $235k awarded
m6A mRNA reader proteins in the AIDS-opportunistic pathogen Toxoplasma gondii
- NIH R21AI167662Nov 2021 – Oct 2024 · $230k awarded
Regulation of cyst formation in the AIDS opportunistic pathogen Toxoplasma
- NIH R01AI124723Mar 2016 – Feb 2023 · $394k awarded
Translational control during stage conversion of Toxoplasma, an opportunistic infection of HIV/AIDS
- NIH R21AI150616Mar 2020 – Feb 2023 · $230k awarded
Eradicating latent toxoplasmosis
- NIH R21AI152583Jan 2020 – Dec 2022 · $230k awarded
GCN5a and cyst development in the AIDS-opportunistic pathogen Toxoplasma
- NIH R21AI145239Mar 2019 – Feb 2022 · $233k awarded
Epitranscriptomics in the AIDS-opportunistic pathogen Toxoplasma gondii
- NIH R01AI116496Dec 2014 – Nov 2021 · $386k awarded
The GCN5b acetylation complex in the AIDS pathogen Toxoplasma
- NIH R21AI125822Jun 2016 – May 2019 · $195k awarded
Elucidating new and old roles for autophagy-like proteins in Toxoplasma gondii
- NIH R21AI106435Jan 2013 – Dec 2016 · $234k awarded
Manipulation of host cell acetylome in AIDS opportunistic infection
- NIH R21AI105786Aug 2013 – Jul 2016 · $229k awarded
Inhibition of phosphatase activity as a novel treatment for chronic toxoplasmosis
- NIH R01AI077502May 2009 – Apr 2016 · $355k awarded
GCN5-mediated transcription in AIDS pathogen Toxoplasma
- NIH R21AI083732Jul 2009 – Jun 2012 · $231k awarded
MYST opportunities for Toxoplasma drug development
- NIH R21AI084031Jun 2009 – May 2012 · $191k awarded
Translational control and latent Toxoplasma infection
- NIH R21AI073091Jul 2007 – Jun 2010 · $223k awarded
APEs as novel drug targets in AIDS opportunistic pathogen Toxoplasma
- NIH R56AI077502Dec 2001 – Apr 2009 · $308k awarded
GCN5-mediated transcription in AIDS pathogen Toxoplasma
- NIH R01GM065051Feb 2003 – Aug 2008 · $243k awarded
GCN5-mediated transcription in AIDS pathogen Toxoplasma
Matched to public NIH RePORTER and NSF records by name and institution. Awards from other agencies are not shown, and a match is not always found — this list may be incomplete.
Typically publishes in teams of ~6 · 22% small-team papers (≤3 authors) · across 34 venues
- Large scale quantification of natural killer cell-induced apoptosis in patient-derived organoids reveals intratumoral response heterogeneity
npj Precision Oncology · 2025
- Detection of Toxoplasma gondii in Brain Tissues of Pet Birds with Neurological Symptoms Using Loop-Mediated Isothermal Amplification (LAMP) and PCR
Acta Parasitologica · 2025
- A patient-derived ovarian cancer organoid platform to study susceptibility to natural killer cells
bioRxiv (Cold Spring Harbor Laboratory) · 2025
- <i>Toxoplasma gondii</i> RAD51 recombinase is required to overcome DNA replication stress and its inactivation leads to bradyzoite differentiation
bioRxiv (Cold Spring Harbor Laboratory) · 2025
- Toxoplasma gondii RAD51 recombinase is required to overcome DNA replication stress and its inactivation leads to bradyzoite differentiation
DNA repair · 2025
- Modeling of Intracellular Taurine Levels Associated with Ovarian Cancer Reveals Activation of p53, ERK, mTOR and DNA-Damage-Sensing-Dependent Cell Protection
Nutrients · 2024
- Detection of Toxoplasma Gondii in the Brain of Pet Birds by Seizures with Loop-Mediated Isothermal Amplification (LAMP)
Research Square · 2024
- Histone variant H2B.Z acetylation is necessary for maintenance of Toxoplasma gondii biological fitness
Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms · 2023
- Evaluation of topotecan and 10-hydroxycamptothecin on Toxoplasma gondii: Implications on baseline DNA damage and repair efficiency
International Journal for Parasitology Drugs and Drug Resistance · 2023
- Modeling of Intracellular Taurine Levels Associated with Ovarian Cancer Reveals Activation of p53, ERK, mTOR and DNA-damage-sensing-dependent Cell Protection
bioRxiv (Cold Spring Harbor Laboratory) · 2023
- Histone Variant H2B.Z Acetylation is Necessary for Maintenance of Toxoplasma Gondii Biological Fitness
SSRN Electronic Journal · 2023
- Histone variant H2B.Z acetylation is necessary for maintenance of <i>Toxoplasma gondii</i> biological fitness
bioRxiv (Cold Spring Harbor Laboratory) · 2023
- Genome-wide localization of histone variants in Toxoplasma gondii implicates variant exchange in stage-specific gene expression
BMC Genomics · 2022
- Eukaryotic Initiation Factor 2α Kinases Regulate Virulence Functions, Stage Conversion, and the Stress Response in Entamoeba invadens
mSphere · 2022
- Eukaryotic initiation factor 2α kinases regulate virulence functions, stage conversion, and the stress response in <i>Entamoeba invadens</i>
bioRxiv (Cold Spring Harbor Laboratory) · 2022
- PMC×18
- bioRxiv (Cold Spring Harbor Laboratory)×17
- mSphere×8
- mBio×4
- Antimicrobial Agents and Chemotherapy×4
- My‐Hang Huynh
Immunology and Microbiology · University of Michigan
- Michael J. Holmes
Immunology and Microbiology · Indiana University
- Vern B. Carruthers
Immunology and Microbiology · University of Michigan
- Gustavo Arrizabalaga
Immunology and Microbiology · Indiana University
- Vernon Carruthers
Immunology and Microbiology · University of Michigan
This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.
Last updated Sep 1, 2026.
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