Vincent Nganga
Immunology and Microbiology · The Ohio State University
Publications
26
Citations
437
Est. group size
—
Recurring co-author estimate
Active years
16
Publishing since 2010
Vincent Nganga studies how immune cells called T cells develop, focusing on how the physical folding and looping of DNA in the genome controls the assembly of antigen receptor genes (the molecular tags T cells use to recognize threats). The work combines genomics, chromatin biology (how DNA is packaged and organized in 3D), and immunology, including studies of leukemia cell models and gene-editing tools like synthetic zinc finger proteins to manipulate gene activity.
Publication output was sparse or absent in the earlier part of the decade but has increased in the most recent two years (2024-2025), suggesting a recent uptick in activity.
Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026
- Promoter- and enhancer-dependent cohesin loading initiates chromosome looping to fold Tcrb loci for long-range recombination
Cell Reports · 2025
- Locus folding mechanisms determine modes of antigen receptor gene assembly
immuneACCESS · 2025
- Abstract 2283 Modulation of Super-Enhancer Activity in T-ALL JURKAT Cells Utilizing Synthetic Zinc Finger Proteins
Journal of Biological Chemistry · 2025
- Locus folding mechanisms determine modes of antigen receptor gene assembly
The Journal of Experimental Medicine · 2024
- Notch1 sets the molecular clock for T cell development
Research Square · 2024
- Promoter- and Enhancer-Dependent Cohesin Loading Initiates Chromosome Looping to Fold <i>Tcrb</i> Loci for Long-Range Recombination
bioRxiv (Cold Spring Harbor Laboratory) · 2024
- Abstract 2064: Modulation of TAL1 Gene Expression in T-ALL JURKAT Cells Using Synthetic Zinc Finger DNA-Binding Proteins
Journal of Biological Chemistry · 2023
- Topological and transcriptional control of TCRβ antigen receptor diversification
The Journal of Immunology · 2021
- Elucidating Topological Regulation of Antigen Receptor Gene Assembly
The Journal of Immunology · 2020
- The role CTCF and transcription in sculpting the TCRβ repertoire
The Journal of Immunology · 2018
- The Journal of Immunology×4
- Journal of Biological Chemistry×2
- Nature Communications×1
- The Journal of Experimental Medicine×1
- Cell Reports×1
- William H. Marshall
Immunology and Microbiology · The Ohio State University
- Daniel Jasinski
Immunology and Microbiology · The Ohio State University
- Amy E. Lovett‐Racke
Immunology and Microbiology · The Ohio State University
- Billur Akkaya
Immunology and Microbiology · The Ohio State University
- G. E. Moore
Immunology and Microbiology · Purdue University West Lafayette
This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.
Last updated Jul 19, 2026.
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