Tyler Shugg
Pharmacology, Toxicology and Pharmaceutics · Indiana University
Publications
45
Citations
387
Est. group size
—
Recurring co-author estimate
Active years
17
Publishing since 2010
Tyler Shugg studies how genetics and drug interactions affect the heart, with a focus on the electrical signals (ion channels) that control heart rhythm and how medications influence them. The work spans pharmacogenetics (how a person's genes affect their response to drugs), heart failure treatment outcomes, and drug-induced heart rhythm problems. Recent work also explores using real-world patient data to improve dosing in special populations.
Publication activity has grown over the last decade, rising from a few papers per year early on to a steady output of roughly six per year in recent years.
Generated by claude-opus-4-8 from public bibliographic data · Jul 11, 2026
- Integrating Real-World Data and Pharmacometrics to Bridge Evidence Gaps in Special Populations: A State-of-the-Art Review
Pharmaceutics · 2026
- Factors Associated With the Recovery of Left Ventricular Ejection Fraction in Patients With Anthracycline-Induced Left Ventricular Dysfunction
Journal of Cardiovascular Pharmacology and Therapeutics · 2025
- Prevalence and types of inconsistencies in clinical pharmacogenetic recommendations among major U.S. sources
npj Genomic Medicine · 2020
- Neurohormonal Regulation of I <sub>Ks</sub> in Heart Failure: Implications for Ventricular Arrhythmogenesis and Sudden Cardiac Death
Journal of the American Heart Association · 2020
- Letrozole targets the human ether‐a‐go‐go–related gene potassium current in glioblastoma
Basic & Clinical Pharmacology & Toxicology · 2020
- Inhibition of Human Ether-A-Go-Go-Related Gene (hERG) Potassium Current by the Novel Sotalol Analogue, Soestalol
JACC. Clinical electrophysiology · 2020
- Association of Regulatory Genetic Variants for Protein Kinase Cα with Mortality and Drug Efficacy in Patients with Heart Failure
Cardiovascular Drugs and Therapy · 2019
- GENOME-WIDE ASSOCIATION STUDY OF MORTALITY BENEFIT FROM BETA-BLOCKERS IN PATIENTS WITH HEART FAILURE WITH REDUCED EJECTION FRACTION
Journal of the American College of Cardiology · 2019
- Calcium/calmodulin-dependent protein kinase II regulation of IKs during sustained β-adrenergic receptor stimulation
Heart Rhythm · 2018
- Calcium/Calmodulin-Dependent Protein Kinase II Regulation of IKs during Sustained Beta-Adrenergic Receptor Stimulation
Author eBooks · 2018
- Chapter 3: Factors Contributing to Drug-Induced Diseases
American Society of Health-System Pharmacists eBooks · 2018
- Abstract 20459: Calcium/Calmodulin-Dependent Protein Kinase II Regulates KCNQ1 to Reduce the Slow Component of the Delayed Rectifier Potassium Current, IKs
Circulation · 2016
- Clinical Pharmacology & Therapeutics×5
- medRxiv×3
- JCO Precision Oncology×2
- Frontiers in Oncology×2
- The Journal of Clinical Pharmacology×2
This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.
Last updated Jul 11, 2026.
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