Timothy F. Plageman
Biochemistry, Genetics and Molecular Biology · The Ohio State University
Publications
33
Citations
1,034
Est. group size
—
Recurring co-author estimate
Active years
23
Publishing since 2004
Timothy F. Plageman studies how cells change shape and organize themselves during the development of tissues such as the eye lens, heart, and thyroid, using mouse models and genetic approaches. Much of the work focuses on genes like Shroom3, Arvcf, and Cdc42 that control cell junctions, polarity, and tissue folding, connecting basic developmental biology to congenital conditions like cataracts and heart defects. This research is relevant to students interested in genetics, developmental biology, and the cellular mechanisms behind birth defects.
Publication output has been modest and uneven over the last decade, with a peak in 2019 and a recent slight uptick in 2025, averaging just over one paper per year in the last five years.
Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026
- Genome-wide association mapping and targeted loss of function studies identify <i>Shroom3</i> as a driver of hyperpolyploidy and ventricular dilation
Proceedings of the National Academy of Sciences · 2026
- Shroom3 facilitates optic fissure closure via tissue alignment and reestablishment of apical-basal polarity during epithelial fusion
Developmental Biology · 2025
- Understanding the role of Shroom3 in the developing mouse myocardium
PLoS ONE · 2025
- Mapping Shroom3 expression across the adult mouse
Gene Expression Patterns · 2025
- Lens Induction: Specification, Determination, and Placode Morphogenesis
Elsevier eBooks · 2024
- Arvcf Dependent Adherens Junction Stability is Required to Prevent Age-Related Cortical Cataracts
Frontiers in Cell and Developmental Biology · 2022
- Arvcf maintains lens transparency through the stability of the adherens junctional complex in lens fiber cells
Investigative Ophthalmology & Visual Science · 2021
- Formation and contraction of multicellular actomyosin cables facilitate lens placode invagination
Developmental Biology · 2020
- Lens Stretching Modulates Lens Epithelial Cell Proliferation via YAP Regulation
Investigative Ophthalmology & Visual Science · 2019
- Novel variants in <i>CDH2</i> are associated with a new syndrome including Peters anomaly
Clinical Genetics · 2019
- Folic acid modifies the shape of epithelial cells during morphogenesis via a Folr1 and MLCK dependent mechanism
Biology Open · 2019
- Author response for "Novel variants in <i>CDH2</i> are associated with a new syndrome including Peters anomaly"
2019
- Identifying the mechanisms of centripetal movement of lens placodal cells during invagination.
Investigative Ophthalmology & Visual Science · 2019
- The non-canonical Wnt-PCP pathway shapes the caudal neural plate
Development · 2018
- <i>KCNA4</i> deficiency leads to a syndrome of abnormal striatum, congenital cataract and intellectual disability
Journal of Medical Genetics · 2016
- Investigative Ophthalmology & Visual Science×4
- Developmental Biology×3
- Biology Open×2
- Development×1
- Journal of Medical Genetics×1
- Catherine Cheng
Biochemistry, Genetics and Molecular Biology · Indiana University
- Shigeo Tamiya
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- Segewkal Heruye
Biochemistry, Genetics and Molecular Biology · Indiana University
- Elizabeth S. Yeh
Biochemistry, Genetics and Molecular Biology · Indiana University
- Michelle R. Emond
Biochemistry, Genetics and Molecular Biology · The Ohio State University
This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.
Last updated Jul 19, 2026.
Claim or correct this profile