Steven S. Welc
Biochemistry, Genetics and Molecular Biology · Indiana University
Publications
44
Citations
1,121
Est. group size
—
Recurring co-author estimate
Active years
17
Publishing since 2010
Steven S. Welc studies how skeletal muscle repairs itself and how this process changes in disease and aging. Much of the work focuses on the immune system's role—particularly immune cells called macrophages—in either helping or harming muscle regeneration, with applications to conditions like Duchenne muscular dystrophy, age-related muscle loss (sarcopenia), and muscle-bone interactions in kidney disease.
Publication activity has grown noticeably in recent years, rising from one or two papers annually to five in 2024 and seven in 2025.
Generated by claude-opus-4-8 from public bibliographic data · Jul 11, 2026
- BACH2 links β1-adrenergic receptor/β-arrestin1 signaling to MIAT to inhibit cardiac fibroblast activation and cardiomyocyte apoptosis
Cell Death Discovery · 2026
- Multi-tissue spatial transcriptomics identified simultaneous responses to oxidative stress and apoptosis in parallel with tissue-specific reprogramming in modeled chronic kidney disease-mineral and bone disorder
JBMR Plus · 2025
- Adaptable Immunofluorescence Protocol for Muscle Fiber Typing in FFPE Human and Mouse Skeletal Muscle and Intact Mouse Hindlimbs
Current Protocols · 2025
- Aging: A struggle for beneficial to overcome negative factors made by muscle and bone
Mechanisms of Ageing and Development · 2025
- Cytotoxic T-Lymphocyte–Associated Protein 4 Fused to a Modified Fragment of IgG1 Reduces Muscle Fiber Damage in a Model of Duchenne Muscular Dystrophy by Attenuating Proinflammatory Gene Expression in Myeloid Lineage Cells
American Journal Of Pathology · 2025
- Simultaneous Transcriptional Reprogramming in Cortical Bone, Muscle, and Bone Marrow Uncovered by Spatial Transcriptomics in Modeled CKD
Journal of the American Society of Nephrology · 2024
- Myeloid cell‐specific mutation of <i>Spi1</i> selectively reduces <scp>M2</scp>‐biased macrophage numbers in skeletal muscle, reduces age‐related muscle fibrosis and prevents sarcopenia
Aging Cell · 2022
- Myeloid cell-mediated targeting of LIF to dystrophic muscle causes transient increases in muscle fiber lesions by disrupting the recruitment and dispersion of macrophages in muscle
Human Molecular Genetics · 2021
- Aging of the immune system and impaired muscle regeneration: A failure of immunomodulation of adult myogenesis
Experimental Gerontology · 2020
- Differential Effects of Myeloid Cell PPARδ and IL-10 in Regulating Macrophage Recruitment, Phenotype, and Regeneration following Acute Muscle Injury
The Journal of Immunology · 2020
- Modulation of Klotho expression in injured muscle perturbs Wnt signalling and influences the rate of muscle growth
2020
- Modulation of Klotho expression in injured muscle perturbs Wnt signalling and influences the rate of muscle growth
Experimental Physiology · 2019
- Targeting a therapeutic LIF transgene to muscle via the immune system ameliorates muscular dystrophy
Nature Communications · 2019
- Aging of the immune system causes reductions in muscle stem cell populations, promotes their shift to a fibrogenic phenotype, and modulates sarcopenia
The FASEB Journal · 2018
- Myeloid cell‐derived tumor necrosis factor‐alpha promotes sarcopenia and regulates muscle cell fusion with aging muscle fibers
Aging Cell · 2018
- Human Molecular Genetics×4
- bioRxiv (Cold Spring Harbor Laboratory)×3
- The FASEB Journal×2
- Aging Cell×2
- Comprehensive physiology×2
This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.
Last updated Jul 11, 2026.
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