Steven D. Goodman
Biochemistry, Genetics and Molecular Biology · The Ohio State University
Publications
112
Citations
4,428
Est. group size
~1
Recurring co-author estimate
Active years
40
Publishing since 1986
This researcher studies bacterial biofilms — protective communities of bacteria embedded in a matrix of extracellular DNA and proteins — and how disrupting this matrix can make infections more vulnerable to antibiotics and the immune system. Much of the work focuses on nucleoid-associated proteins (like HMGB1 and DNABII proteins) that hold biofilms together, and on engineered peptides or antibodies that break down biofilms in respiratory pathogens such as nontuberculous mycobacteria and Haemophilus influenzae. Some publications also touch on DNA repair enzymes and unrelated topics such as meteorology and neonatal necrotizing enterocolitis, suggesting occasional collaborative or tangential contributions.
Publication output has fluctuated over the last decade, peaking in 2021 (12 papers) with a recent uptick in 2025 (8 papers) after a slower 2023-2024 period.
Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026
- Mycobacterium abscessus biofilm cleared from murine lung by monoclonal antibody against bacterial DNABII proteins
Journal of Cystic Fibrosis · 2025
- Bacterial biofilm-derived H-NS protein acts as a defense against Neutrophil Extracellular Traps (NETs)
npj Biofilms and Microbiomes · 2025
- High-mobility group protein B1 derived mutant peptide mB Box-97 inhibits the formation of neutrophil extracellular traps
Frontiers in Immunology · 2025
- An engineered peptide derived from the innate immune effector high-mobility group box 1 disrupts and prevents dual-genera biofilms formed by common respiratory tract pathogens
FEMS Microbiology Letters · 2025
- The Nucleoid Proteins Fis and IHF Positively Regulate the Gene Expression of Operons Responsible for Producing the Cytotoxins Tilimycin and Tilivalline in <i>Klebsiella oxytoca</i>
International Journal of Microbiology · 2025
- Proofreading of mismatches within primer-template junctions by Escherichia coli DNA polymerase I in vitro and in vivo
DNA repair · 2025
- Human PMNs exhibit greater engulfment, NETosis, and enhanced migration when incubated with nontypeable Haemophilus influenzae newly released from a biofilm
Frontiers in Microbiology · 2025
- Extracellular DNA-protein interactions
Current Opinion in Structural Biology · 2024
- Noninflammatory 97-amino acid High Mobility Group Box 1 derived polypeptide disrupts and prevents diverse biofilms
EBioMedicine · 2024
- Corrigendum: ESKAPEE pathogens newly released from biofilm residence by a targeted monoclonal are sensitized to killing by traditional antibiotics
Frontiers in Microbiology · 2024
- ESKAPEE pathogens newly released from biofilm residence by a targeted monoclonal are sensitized to killing by traditional antibiotics
Frontiers in Microbiology · 2023
- Disruption of nontuberculous mycobacteria biofilms induces a highly vulnerable to antibiotic killing phenotype
Biofilm · 2023
- Introduction
Bulletin of the American Meteorological Society · 2023
- Uracil-DNA Glycosylase Assay by Matrix-assisted Laser Desorption/Ionization Time-of-flight Mass Spectrometry Analysis
Journal of Visualized Experiments · 2022
- Bacterial Biofilms Utilize an Underlying Extracellular DNA Matrix Structure That Can Be Targeted for Biofilm Resolution
Microorganisms · 2022
- DNA repair×5
- Frontiers in Microbiology×4
- Journal of Visualized Experiments×4
- Microscopy and Microanalysis×3
- Bulletin of the American Meteorological Society×2
- Stephen D. Bell
Biochemistry, Genetics and Molecular Biology · Indiana University
- Charles E. Bell
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- Rachel Y. Samson
Biochemistry, Genetics and Molecular Biology · Indiana University
- Gail G. Hardy
Biochemistry, Genetics and Molecular Biology · Indiana University
- Jennifer L. Greenwich
Biochemistry, Genetics and Molecular Biology · Indiana University
This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.
Last updated Jul 19, 2026.
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