Stephen R. Byrn
Materials Science · Purdue University West Lafayette
Publications
242
Citations
8,199
Est. group size
~5
Recurring co-author estimate
Active years
60
Publishing since 1967
Stephen R. Byrn's research focuses on the physical and chemical properties of pharmaceutical solids, particularly how drug molecules organize themselves in crystalline and amorphous (non-crystalline, glass-like) forms. His work uses X-ray diffraction and related structural techniques to understand drug solubility, stability, and formulation behavior, which are important for designing effective oral medications. Much of the recent work involves amorphous solid dispersions, where a drug is mixed with a polymer to improve its solubility and delivery.
Publication output has fluctuated over the last decade with notable peaks in 2021 and 2024, suggesting an active but variable rather than steadily growing or slowing output.
Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026
- The Molecular Structures of Liquid and Glassy Nifedipine and Felodipine and Their Incorporation into PVP
Pharmaceuticals · 2026
- Modeling the Structure of Ketoprofen-Poly(vinylpyrrolidone) Amorphous Solid Dispersions with Empirical Potential Structure Refinements of X-ray Scattering Data
Molecular Pharmaceutics · 2024
- Molecular structure of ketoprofen-polyvinylpyrrolidone solid dispersions prepared by different amorphization methods
RSC Pharmaceutics · 2024
- Hydrogen Bonding in Amorphous Indomethacin
Preprints.org · 2024
- Accelerated Development of Pharmaceuticals Past, Present, and Future
Pharmaceutical Research · 2024
- Polymorphism in Erlotinib Hydrochloride: New Insights into Relative Stability, Thermal Behavior, and Structural Differences of Forms A and B
Crystal Growth & Design · 2023
- Hot-melt extrudability of amorphous solid dispersions of flubendazole-copovidone: An exploratory study of the effect of drug loading and the balance of adjuvants on extrudability and dissolution
International Journal of Pharmaceutics · 2022
- Ritonavir Form III: Lightning strikes twice at the same time, 137 miles apart
ChemRxiv · 2022
- Acoustic levitation and high-resolution synchrotron X-ray powder diffraction: A fast screening approach of niclosamide amorphous solid dispersions
International Journal of Pharmaceutics · 2021
- Amorphous dispersions of flubendazole in hydroxypropyl methylcellulose: Formulation stability assisted by pair distribution function analysis
International Journal of Pharmaceutics · 2021
- Evaluation of tableting performance of Poly (ethylene oxide) in abuse-deterrent formulations using compaction simulation studies
Journal of Pharmaceutical Sciences · 2021
- Contribution to the Improvement of an Oral Formulation of Niclosamide, an Antihelmintic Drug Candidate for Repurposing in SARS-CoV-2 and Other Viruses
ChemRxiv · 2020
- Contribution to the Improvement of an Oral Formulation of Niclosamide, an Antihelmintic Drug Candidate for Repurposing in SARS-CoV-2 and Other Viruses
ChemRxiv · 2020
- Predictive and Accelerated Formulation Design Using Synchrotron Methods
AAPS PharmSciTech · 2019
- Continuity of solids between amorphous and crystalline states – insights from synchrotron X-ray pair distribution function (SXPDF) studies
Acta Crystallographica Section A Foundations and Advances · 2019
- AAPS PharmSciTech×9
- The Proceedings of the BIRS Community×9
- Molecular Pharmaceutics×8
- ChemRxiv×6
- International Journal of Pharmaceutics×5
- Geoff G. Z. Zhang
Materials Science · Purdue University West Lafayette
- Changquan Calvin Sun
Materials Science · Purdue University West Lafayette
- Mercy A. Okezue
Materials Science · Purdue University West Lafayette
- Tonglei Li
Materials Science · Purdue University West Lafayette
- Na Li
Materials Science · Purdue University West Lafayette
This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.
Last updated Jul 20, 2026.
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