Stephanie N. Oprescu
Biochemistry, Genetics and Molecular Biology · Purdue University West Lafayette
Publications
38
Citations
1,037
Est. group size
~9
Recurring co-author estimate
Active years
60
Publishing since 1967
Stephanie N. Oprescu studies how skeletal muscle forms, regenerates, and is affected by disease, with a focus on muscle stem cells (satellite cells) and the genes that regulate their function. Her work also spans genetic disease research, particularly mutations in aminoacyl-tRNA synthetase genes (enzymes needed for building proteins) that cause inherited neurological and developmental disorders. This combination of muscle biology and rare disease genetics is often approached using single-cell RNA-sequencing and model organisms to understand cell-level mechanisms.
Publication output has been fairly steady over the last decade, averaging a few papers per year with a peak in 2023, and continuing at a similar pace (about 3-4 per year) through 2025-2026.
Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026
- ASB5 is a specific marker for muscle satellite cells but dispensable for skeletal muscle development and regeneration
Skeletal Muscle · 2026
- Stage-specific and cell-autonomous functions of Delta-like 1 in skeletal muscle stem cells and myogenesis
Nature Communications · 2025
- Muscle stem cells as immunomodulator during regeneration
Current topics in developmental biology/Current Topics in Developmental Biology · 2024
- Predictive modeling provides insight into the clinical heterogeneity associated with <i>TARS1</i> loss-of-function mutations
bioRxiv (Cold Spring Harbor Laboratory) · 2024
- A model organism pipeline provides insight into the clinical heterogeneity of TARS1 loss-of-function variants
Human Genetics and Genomics Advances · 2024
- A single‐cell atlas of bovine skeletal muscle reveals mechanisms regulating intramuscular adipogenesis and fibrogenesis
Journal of Cachexia Sarcopenia and Muscle · 2023
- Sox11 is enriched in myogenic progenitors but dispensable for development and regeneration of the skeletal muscle
Skeletal Muscle · 2023
- Sox11 is enriched in myogenic progenitors but dispensable for development and regeneration of skeletal muscle
bioRxiv (Cold Spring Harbor Laboratory) · 2023
- ACSS3 in brown fat drives propionate catabolism and its deficiency leads to autophagy and systemic metabolic dysfunction
Clinical and Translational Medicine · 2022
- 193 Single Cell RNA-sequencing Reveals a Role of Lipid Metabolism in Muscle Satellite Cells
Journal of Animal Science · 2021
- Single-Cell Isolation from Regenerating Murine Muscles for RNA-Sequencing Analysis
STAR Protocols · 2020
- Loss-of-function mutations in Lysyl-tRNA synthetase cause various leukoencephalopathy phenotypes
Neurology Genetics · 2019
- Compound heterozygosity for loss-of-function <i>FARSB</i> variants in a patient with classic features of recessive aminoacyl-tRNA synthetase-related disease
Human Mutation · 2018
- Hypermorphic and hypomorphic AARS alleles in patients with CMT2N expand clinical and molecular heterogeneities
Human Molecular Genetics · 2018
- Cover Image, Volume 39, Issue 3
Human Mutation · 2018
- Human Mutation×5
- bioRxiv (Cold Spring Harbor Laboratory)×4
- iScience×2
- Cell Reports×2
- Nature Communications×2
- Nicolas Wein
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- Nizar Y. Saad
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- Liubov V. Gushchina
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- K. Flanigan
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- E. Frair
Biochemistry, Genetics and Molecular Biology · The Ohio State University
This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.
Last updated Jul 20, 2026.
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