Publications
150
Citations
3,248
Est. group size
~3
Recurring co-author estimate
Active years
43
Publishing since 1984
This researcher works on gene editing and gene therapy approaches for cystic fibrosis, focusing on correcting the CFTR gene in airway and stem cells using tools like CRISPR-Cas9 and adeno-associated virus (AAV) delivery. A separate strand of the publication record involves head and neck cancer imaging and treatment response assessment, suggesting either a shared name across two distinct research areas or a dual clinical-research focus. The CFTR-related work emphasizes improving efficiency and safety of gene correction techniques for potential future therapies.
Publication output has fluctuated over the last decade with peaks around 2018-2019 and 2024, but has slowed in the most recent two years (2025-2026) based on available data.
Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026
- Analysis of the Genome Aggregation Database (gnomAD) reveals a global burden of cystic fibrosis and the need for improved diagnosis and care
EBioMedicine · 2026
- Local Airway Mechanical Preconditioning Enables Efficient Long-Term Airway Epithelial Reconstitution with Gene-Edited Cells that Restore Ion Transport in Cystic Fibrosis Models
SSRN Electronic Journal · 2026
- Highly efficient in vivo hematopoietic stem cell transduction using an optimized self-complementary adeno-associated virus
Molecular Therapy — Methods & Clinical Development · 2025
- Durable reconstitution of sinonasal epithelium by transplant of CFTR gene corrected airway stem cells
bioRxiv (Cold Spring Harbor Laboratory) · 2025
- 279 Simultaneous inhibition of DNA-PKcs and 53BP1 enables the enrichment-free replacement of the CFTR cDNA in airway basal stem cells
Journal of Cystic Fibrosis · 2025
- Head and Neck Cancer: United Kingdom National Multidisciplinary Guidelines, Sixth Edition
The Journal of Laryngology & Otology · 2024
- Investigating adverse genomic and regulatory changes caused by replacement of the full-length CFTR cDNA using Cas9 and AAV
Molecular Therapy — Nucleic Acids · 2024
- Homeostatic Role of Decorin in Right Ventricular Pressure Overload and Pulmonary Hypertension Induced Remodeling
JACC Basic to Translational Science · 2024
- Targeted replacement of full-length CFTR in human airway stem cells by CRISPR-Cas9 for pan-mutation correction in the endogenous locus
UNC Libraries · 2024
- High-efficiency transgene integration by homology-directed repair in human primary cells using DNA-PKcs inhibition
Nature Biotechnology · 2023
- Clinical Utility of Second-Look FDG PET-CT to Stratify Incomplete Metabolic Response Post (Chemo) Radiotherapy in Oropharyngeal Squamous Cell Carcinoma
Cancers · 2023
- 272 Preclinical development of an autologous stem cell gene therapy platform for treatment of cystic fibrosis sinus and upper airway disease
Journal of Cystic Fibrosis · 2023
- Single-Stranded DNA with Internal Base Modifications Mediates Highly Efficient Gene Insertion in Primary Cells
Zenodo (CERN European Organization for Nuclear Research) · 2023
- Single-Stranded DNA with Internal Base Modifications Mediates Highly Efficient Gene Insertion in Primary Cells
Zenodo (CERN European Organization for Nuclear Research) · 2023
- CFTR genotype analysis of Asians in international registries highlights disparities in the diagnosis and treatment of Asian patients with cystic fibrosis
Genetics in Medicine · 2022
- Clinical Radiology×6
- bioRxiv (Cold Spring Harbor Laboratory)×6
- Molecular Therapy — Nucleic Acids×4
- Journal of Cystic Fibrosis×4
- Molecular Therapy×3
- Kirsten M. Kloepfer
Medicine · Indiana University
- B H Davies
Medicine · The Ohio State University
- Baohua Zhou
Medicine · Indiana University
- Mitchell H. Grayson
Medicine · The Ohio State University
- Anushka Ruwanpathirana
Medicine · The Ohio State University
This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.
Last updated Jul 19, 2026.
Claim or correct this profile