Shili Lin
Biochemistry, Genetics and Molecular Biology · The Ohio State University
Publications
244
Citations
3,941
Est. group size
~6
Recurring co-author estimate
Active years
34
Publishing since 1993
Shili Lin develops statistical and computational methods for analyzing genomic data, with a particular focus on Hi-C data, which measures how DNA folds and organizes itself in three dimensions inside the cell nucleus. This work involves building models and software to detect patterns like chromatin loops, compare cell subtypes, and combine different genomic data types (such as single-cell Hi-C and RNA-seq) to understand how genome structure relates to gene activity and disease, including cancer. The group also works on statistical methods for genetic association studies, including detecting disease-related genetic patterns using family and population data.
Publication output has fluctuated over the last decade with peaks in 2020 and 2023, and while recent years (2024-2026) show somewhat lower counts, the 5-year average of about 10 publications per year suggests continued steady activity.
Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026
- szKendall: spatial-structural-zero-aware dissimilarity measures for subtype discovery using single cell Hi-C data
Nature Communications · 2026
- Interview With Professor Elizabeth A. Thompson
International Statistical Review · 2026
- A divide and conquer strategy for recapitulating whole genome 3D structure using Hi-C data
Biostatistics · 2026
- Can random walking on a Hi-C contact matrix lead to data quality improvement? An assessment
PLoS ONE · 2025
- Can Random Walking on a Hi-C Contact Matrix Lead to Data Quality Improvement? An Assessment
bioRxiv (Cold Spring Harbor Laboratory) · 2025
- Novel Spatial-Structural-Zero-Aware Dissimilarity Measures for Subtype Discovery Using Single Cell Hi-C Data
bioRxiv (Cold Spring Harbor Laboratory) · 2025
- Integration of scHi-C and scRNA-seq data defines distinct 3D-regulated and biological-context dependent cell subpopulations
Nature Communications · 2024
- An in silico procedure for generating protein-mediated chromatin interaction data and comparison of significant interaction calling methods
PLoS ONE · 2024
- Sparse Estimation in Semiparametric Finite Mixture of Varying Coefficient Regression Models
Biometrics · 2023
- BCurve: Bayesian Curve Credible Bands Approach for the Detection of Differentially Methylated Regions
Methods in molecular biology · 2022
- Modeling and analysis of Hi-C data by HiSIF identifies characteristic promoter-distal loops
Genome Medicine · 2020
- Characterization of histone modification patterns and prediction of novel promoters using functional principal component analysis
PLoS ONE · 2020
- Incorporating information from markers in LD with test locus for detecting imprinting and maternal effects
European Journal of Human Genetics · 2020
- Detecting rare haplotypes associated with complex diseases using both population and family data: Combined logistic Bayesian Lasso
Statistical Methods in Medical Research · 2020
- Author Correction: Temporal dynamic reorganization of 3D chromatin architecture in hormone-induced breast cancer and endocrine resistance
Nature Communications · 2020
- Figshare×7
- bioRxiv (Cold Spring Harbor Laboratory)×6
- Nature Communications×4
- Biometrics×3
- Statistics in Biosciences×3
- Nianjun Liu
Biochemistry, Genetics and Molecular Biology · Indiana University
- Geyu Zhou
Biochemistry, Genetics and Molecular Biology · Purdue University West Lafayette
- Robbee Wedow
Biochemistry, Genetics and Molecular Biology · Indiana University
- Veronica J. Vieland
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- Asuman Turkmen
Biochemistry, Genetics and Molecular Biology · The Ohio State University
This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.
Last updated Jul 19, 2026.
Claim or correct this profile