LabCompass

Seung-Oe Lim

Medicine · Purdue University West Lafayette

OpenAlex
Mid career · publishing since 2008
Cancer Cells and MetastasisEpigenetics and DNA MethylationImmunotherapy and Immune ResponsesCancer Immunotherapy and BiomarkersGlycosylation and Glycoproteins Research

Publications

24

Citations

7,238

Est. group size

—

Recurring co-author estimate

Active years

18

Publishing since 2008

Research summary
AI-generated

Seung-Oe Lim's research focuses on how cancer cells evade the immune system, particularly through regulation of the immune checkpoint protein PD-L1 (a molecule tumors use to suppress immune attack) and related signaling pathways. This work explores molecular mechanisms such as protein modification, signaling cascades, and drug resistance to identify ways to improve cancer immunotherapy, especially in combination treatment strategies. Studies span multiple cancer types including breast, pancreatic, and liver cancer, often using findings to suggest biomarkers or therapeutic targets.

Cancer immune evasion mechanismsPD-L1/PD-1 checkpoint regulationTumor immunotherapy combination strategiesCancer signaling pathways (e.g., IL-6/JAK1, EGFR)Biomarkers for treatment sensitivity

Publication output was concentrated between 2017-2021 with a cluster of papers, followed by a gap and only sporadic output (including one in 2025), indicating a slowing pace in recent years.

Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026

Publication cadence
Publications per year over the last 10 years — averaging 0.2/year recently
2017: 2 publications172018: 3 publications3182019: 2 publications19202021: 1 publication212223242025: 1 publication2526
Recent publications
Publishes in
  • Cancer Cell×3
  • Cancer Research×3
  • Nature Communications×2
  • Journal of Clinical Investigation×2
  • Clinical Cancer Research×1
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By research-topic overlap

This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.

Last updated Jul 20, 2026.

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