Sergio Barajas
Biochemistry, Genetics and Molecular Biology · Indiana University
Publications
17
Citations
159
Est. group size
—
Recurring co-author estimate
Active years
8
Publishing since 2019
Sergio Barajas studies the molecular biology of blood cell formation and blood cancers such as leukemia. The research focuses on how specific proteins (like the phosphatase PRL2/PTP4A2 and the polycomb protein Mel18) and signaling pathways (especially the p53 tumor-suppressor pathway) control the behavior of blood-forming stem cells and drive cancer development. This work combines cancer genetics, epigenetics, and stem cell biology, and includes engineering stem cells for immunotherapy applications.
Publication activity has been steady with a modest increase in recent years, peaking around 2024.
Generated by claude-opus-4-8 from public bibliographic data · Jul 11, 2026
- Abstract LB145: Lentiviral-based hematopoietic stem cell platform for macrophage-specific expression in glioma immunotherapy
Cancer Research · 2026
- PTP4A2 promotes leukemogenesis through inhibiting the p53 tumor suppressor signaling pathway in leukemia-initiating cells
Blood Advances · 2026
- Protein Tyrosine Phosphatase PRL2 Promotes <i>MLL</i>-Rearranged Acute Myeloid Leukemia Development through Inhibiting the p53 Pathway
Blood · 2024
- 3037 – POLYCOMB GROUP PROTEIN MEL18 REGULATES HEMATOPOIETIC STEM CELL BEHAVIORS VIA MODULATING THE EPIGENOME AND HIGHER ORDER CHROMATIN STRUCTURE
Experimental Hematology · 2024
- 3203 – PROTEIN TYROSINE PHOSPHATASE PRL2 PROMOTES MLL-AF9 DRIVEN LEUKEMOGENESIS VIA INHIBITING THE P53 PATHWAY
Experimental Hematology · 2024
- Polycom Group Protein Mel18 Inhibits Hematopoietic Stem Cell Self-Renewal through Repressing the Expression of Genes Important for Cellular Senescence and Proliferation
Blood · 2023
- PRL2 Phosphatase Promotes Oncogenic KIT Signaling in Leukemia Cells through Modulating CBL Phosphorylation
Molecular Cancer Research · 2023
- Chronic Inflammation Drives p53 Mutant Clonal Hematopoiesis Via Activating the NLRP1 Inflammasome
Blood · 2022
- Role of p53 in regulation of hematopoiesis in health and disease
Current Opinion in Hematology · 2022
- Blood×5
- Nature Communications×2
- Experimental Hematology×2
- Journal of Clinical Investigation×1
- Molecular Cancer Research×1
This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.
Last updated Jul 11, 2026.
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