LabCompass

Seema Mattoo

Immunology and Microbiology · Purdue University West Lafayette

OpenAlex ORCID
Established · publishing since 1994
Bacterial Infections and VaccinesEndoplasmic Reticulum Stress and DiseaseBacterial Genetics and BiotechnologyGlycogen Storage Diseases and MyoclonusParkinson's Disease Mechanisms and Treatments

Publications

56

Citations

3,301

Est. group size

—

Recurring co-author estimate

Active years

33

Publishing since 1994

Research summary
AI-generated

Seema Mattoo studies how bacteria manipulate host cells during infection, focusing on bacterial toxins and secreted effector proteins (from organisms like Bordetella, Stenotrophomonas, and Pasteurella) and how they modify host proteins through processes such as AMPylation and phosphorylation. The lab also develops and applies imaging and biochemical tools, including the CryoAPEX electron microscopy method, to visualize where these proteins act inside cells. This work sits at the intersection of microbiology, cell biology, and structural biology, with relevance to understanding infection mechanisms and finding small-molecule inhibitors.

Bacterial toxins and secreted effector proteinsHost-pathogen interactions and immune signalingProtein modification (AMPylation, phosphorylation, adenylylation)Structural and biochemical characterization of enzymesElectron microscopy method development (CryoAPEX)

Publication output peaked around 2019 and has since settled into a more modest but steady pace of about 2 papers per year over the last five years.

Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026

Publication cadence
Publications per year over the last 10 years — averaging 2.0/year recently
2017: 1 publication172018: 4 publications182019: 8 publications8192020: 5 publications202021: 2 publications212022: 1 publication222023: 1 publication232024: 3 publications242025: 4 publications252026: 1 publication26
Recent publications
Publishes in
  • bioRxiv (Cold Spring Harbor Laboratory)×5
  • The FASEB Journal×4
  • BIO-PROTOCOL×3
  • Cell Stress and Chaperones×3
  • Journal of Visualized Experiments×2
Similar researchers
By research-topic overlap

This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.

Last updated Jul 20, 2026.

Claim or correct this profile