Saugat Khanal
Biochemistry, Genetics and Molecular Biology · The Ohio State University
Publications
18
Citations
124
Est. group size
~3
Recurring co-author estimate
Active years
8
Publishing since 2019
Saugat Khanal's research examines how a specific sugar-modification process on proteins, called O-GlcNAcylation (added by the enzyme O-GlcNAc transferase), affects blood vessel cells and heart function in conditions like diabetes, metabolic syndrome, and atherosclerosis (hardening of the arteries). The work uses mouse models to study how this modification influences smooth muscle cell behavior, cognitive decline, and heart rhythm problems, with attention to sex-based differences in disease outcomes.
Publication output grew from none in 2017-2018 to a peak of around 3-4 per year between 2021 and 2024, suggesting a steady, moderate level of research activity in recent years.
Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026
- PO-02-291 NOVEL MECHANISMS UNDERLYING PRO-INFLAMMATORY CYTOKINE IL17A-TRIGGERED ARRHYTHMOGENESIS
Heart Rhythm · 2026
- Deletion of Smooth Muscle O-GlcNAc Transferase Prevents Development of Atherosclerosis in Western Diet-Fed Hyperglycemic ApoE-/- Mice In Vivo
International Journal of Molecular Sciences · 2023
- Cognitive dysfunction and increased phosphorylated tau are associated with reduced <scp>O‐GlcNAc</scp> signaling in an aging mouse model of metabolic syndrome
Journal of Neuroscience Research · 2023
- Deletion of smooth muscle O-GlcNAc transferase prevents development of atherosclerosis in western diet-fed hyperglycemic ApoE <sup>-/-</sup> mice in vivo
bioRxiv (Cold Spring Harbor Laboratory) · 2023
- Abstract P3020: O-GlcNAc Transferase Regulates Vascular Smooth Muscle Cell Cycle Progression In Diabetes
Circulation Research · 2023
- Sex-specific differences in atherosclerosis, thrombospondin-1, and smooth muscle cell differentiation in metabolic syndrome versus non-metabolic syndrome mice
Frontiers in Cardiovascular Medicine · 2022
- Abstract 204: Sex-specific Differences In The Role Of TSP1 On Metabolic Syndrome-induced Atherosclerosis
Arteriosclerosis Thrombosis and Vascular Biology · 2022
- Abstract 135: Sex-specific Differences In The Role Of TSP1 On Metabolic Syndrome-induced Atherosclerosis
Arteriosclerosis Thrombosis and Vascular Biology · 2022
- Leptin in Atherosclerosis: Focus on Macrophages, Endothelial and Smooth Muscle Cells
International Journal of Molecular Sciences · 2021
- Abstract MP48: Smooth Muscle Cell-Specific Deletion Of O-GlcNAc Transferase Impedes Atherosclerotic Lesion Formation In Western Diet-fed Apoe <sup>-/-</sup> Mice
Arteriosclerosis Thrombosis and Vascular Biology · 2021
- Abstract P153: Upregulation Of Thrombospondin-1 Associates With Accelerated Atherosclerosis And Reduced Smooth Muscle Cell Differentiation In Metabolic Syndrome
Arteriosclerosis Thrombosis and Vascular Biology · 2021
- Smooth muscle‐specific deletion of O‐GlcNAc transferase inhibits SMC de‐differentiation in STZ‐induced hyperglycemic mice
The FASEB Journal · 2020
- Alzheimer’s Disease‐Related Pathology and Impaired Cognitive Function Associate with Reduced O‐GlcNAc Transferase in Aged Metabolic Syndrome KKAy <sup>+/−</sup> Mice
The FASEB Journal · 2020
- O‐GlcNAc Transferase Plays a Direct Role in Vascular Smooth Muscle Cell Phenotypic Switching
The FASEB Journal · 2019
- Arteriosclerosis Thrombosis and Vascular Biology×4
- The FASEB Journal×3
- Circulation Research×3
- International Journal of Molecular Sciences×2
- Frontiers in Cardiovascular Medicine×1
- Nicola L. B. Pohl
Biochemistry, Genetics and Molecular Biology · Indiana University
- Chengzhe Gao
Biochemistry, Genetics and Molecular Biology · Purdue University West Lafayette
- Mary Catherine Glick
Biochemistry, Genetics and Molecular Biology · Indiana University
- Jessica Nunes
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- Abram Axelrod
Biochemistry, Genetics and Molecular Biology · Purdue University West Lafayette
This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.
Last updated Jul 19, 2026.
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