Ryan A. Altman
Pharmacology, Toxicology and Pharmaceutics · Purdue University West Lafayette
Publications
132
Citations
3,464
Est. group size
~9
Recurring co-author estimate
Active years
36
Publishing since 1991
Ryan A. Altman's research focuses on organic and medicinal chemistry, particularly the design of new chemical reactions to install fluorine atoms into drug-like molecules. His group develops methods such as difluorination, dearomatization, and catalytic cross-coupling reactions to build complex molecules and improve properties relevant to drug development, like metabolic stability and brain penetration.
Publication output has fluctuated over the last decade but shows an overall upward trend, with a notable peak in 2025 following a dip in 2023.
Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026
- The Effect of <i>N</i> -Alkyl Azole Difluorination on Molecular Properties Relevant for Compound Optimization: A Comparative Study
ACS Medicinal Chemistry Letters · 2026
- NBS-Promoted Synthesis of Maleimides by Oxidative Dearomatization of Pyrroles: Mechanistic Investigations Using Online MS in Real-Time
Organic Letters · 2025
- Enantioselective Total Synthesis of 5-Phenylmorphans and Cis-Octahydroisoquinolines
ChemRxiv · 2025
- Unified Enantioselective Synthesis of 5-Phenylmorphans and <i>cis</i> -Octahydroisoquinolines
Organic Letters · 2025
- Enantioselective Total Synthesis of 5-Phenylmorphans and Cis-Octahydroisoquinolines
ChemRxiv · 2025
- Palladium and copper co-catalyzed chloro-arylation of <i>gem</i> -difluorostyrenes – use of a nitrite additive to suppress β-F elimination
Chemical Science · 2024
- α-Amino-β-carboxymuconate-ε-semialdehyde decarboxylase catalyzes enol/keto tautomerization of oxaloacetate
Journal of Biological Chemistry · 2024
- Peroxide-Initiated Hydrophosphinylation of <i>gem</i>-Difluoroalkenes
The Journal of Organic Chemistry · 2023
- Palladium-Catalyzed Dearomatization of Benzothiophenes: Isolation and Functionalization of a Discrete Dearomatized Intermediate
Synthesis · 2023
- In This Issue, Volume 14, Issue 9
ACS Medicinal Chemistry Letters · 2023
- Fluoroalkylation of Dextromethorphan Improves CNS Exposure and Metabolic Stability
ACS Medicinal Chemistry Letters · 2022
- β-Elimination rules for Pd
Nature Synthesis · 2022
- An Innovation 10 Years in the Making: The Stories in the Pages of <i>ACS Medicinal Chemistry Letters</i>
ACS Medicinal Chemistry Letters · 2022
- In This Issue, Volume 13, Issue 3
ACS Medicinal Chemistry Letters · 2022
- A General Co-Catalytic Hydrothiolation of gem-Difluoroalkenes
ChemRxiv · 2022
- ChemRxiv×16
- ACS Medicinal Chemistry Letters×10
- The Journal of Organic Chemistry×9
- Chemical Communications×3
- Journal of Medicinal Chemistry×3
- Mohammed K. Abd El‐Gaber
Pharmacology, Toxicology and Pharmaceutics · Purdue University West Lafayette
- Shan Jiang
Chemistry · Purdue University West Lafayette
- Pankaj Bhattarai
Pharmacology, Toxicology and Pharmaceutics · Purdue University West Lafayette
- Ankit Kumar
Chemistry · Purdue University West Lafayette
- Mandeep Kaur Hunjan
Chemistry · Purdue University West Lafayette
This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.
Last updated Jul 20, 2026.
Claim or correct this profile