Rui Huang

Biochemistry, Genetics and Molecular Biology · Indiana University

Enzyme Catalysis and Immobilization Biochemical and Molecular Research Metabolism and Genetic Disorders Cyclopropane Reaction Mechanisms Catalytic C–H Functionalization Methods

Publications

Citations

409

Est. group size

—

Recurring co-author estimate

Active years

Publishing since 2012

Research summary

AI-generated

Rui Huang's research centers on protein engineering and enzyme biochemistry, especially designing thermostable enzymes (proteins that remain active at high temperatures) that use coenzymes such as NAD(P). Much of this work supports synthetic biology applications, including in vitro hydrogen production and biobatteries, by reengineering enzyme activity and coenzyme preferences.

Protein and enzyme engineeringThermostable enzymes for biotechnologyCoenzyme (NAD/NADP) engineeringIn vitro hydrogen production and biobatteriesDirected evolution and enzyme screening

Publication activity has been intermittent, with clusters of output around 2017-2018 and 2021 and gaps in several years, averaging under one paper per year over the last five years.

Generated by claude-opus-4-8 from public bibliographic data · Jul 11, 2026

Publication cadence

Publications per year over the last 10 years — averaging 0.8/year recently

Recent publications

Numerical investigation on melting and solidification in a novel bionic honeycomb-fin triple-tube latent heat storage unit with nanoparticle-enhanced PCM
Thermal Science and Engineering Progress · 2025
Coevolution of both Thermostability and Activity of Polyphosphate Glucokinase from Thermobifida fusca YX
Applied and Environmental Microbiology · 2018
Engineering a thermostable highly active glucose 6-phosphate dehydrogenase and its application to hydrogen production in vitro
Applied Microbiology and Biotechnology · 2018
Building a Thermostable Metabolon for Facilitating Coenzyme Transport and In Vitro Hydrogen Production at Elevated Temperature
ChemSusChem · 2018
Cover Feature: Building a Thermostable Metabolon for Facilitating Coenzyme Transport and In Vitro Hydrogen Production at Elevated Temperature (ChemSusChem 18/2018)
ChemSusChem · 2018
Systematic comparison of co-expression of multiple recombinant thermophilic enzymes in Escherichia coli BL21(DE3)
Applied Microbiology and Biotechnology · 2017
Protein engineering of oxidoreductases utilizing nicotinamide-based coenzymes, with applications in synthetic biology
Synthetic and Systems Biotechnology · 2017
Coenzyme engineering of NAD(P)+ dependent dehydrogenases
VTechWorks (Virginia Tech) · 2017
Coenzyme Engineering of a Hyperthermophilic 6-Phosphogluconate Dehydrogenase from NADP+ to NAD+ with Its Application to Biobatteries
Scientific Reports · 2016
High-Throughput Screening of Coenzyme Preference Change of Thermophilic 6-Phosphogluconate Dehydrogenase from NADP+ to NAD+
Scientific Reports · 2016
Facile Construction of Random Gene Mutagenesis Library for Directed Evolution Without the Use of Restriction Enzyme in <i>Escherichia coli</i>
Biotechnology Journal · 2016

Publishes in

Angewandte Chemie International Edition×3
Angewandte Chemie×3
Applied Microbiology and Biotechnology×2
ACS Catalysis×2
Scientific Reports×2

This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.

Last updated Jul 11, 2026.

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