Publications
248
Citations
10,278
Est. group size
~7
Recurring co-author estimate
Active years
38
Publishing since 1989
Riyi Shi's research focuses on how the nervous system is damaged after injuries such as spinal cord injury and traumatic brain injury (including blast-related trauma), with particular attention to a toxic molecule called acrolein and related reactive aldehydes that form after injury and harm nerve cells. The lab also studies oxidative stress and iron overload effects on tissues (including the brain, kidney, colon, and olfactory system), and explores potential therapies to reduce this damage and promote nerve repair. This work is aimed at understanding injury mechanisms and identifying treatments for conditions like spinal cord injury, brain trauma, and related neurodegenerative or inflammatory processes.
Publication output has been fairly steady over the past decade, with a peak around 2021 (12 papers) and a leveling off to about 7 papers per year in recent years.
Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026
- Multimodal Toxicity of Acrolein and Associated Therapeutic Strategies in Central Nervous System Trauma and Disease
Annual Review of Biomedical Engineering · 2026
- Proteomic analysis reveals shared biological pathways linking acrolein to biomolecular changes in the acute phase of rat spinal cord injury
bioRxiv (Cold Spring Harbor Laboratory) · 2026
- Biochemical and Behavioral Analyses Reveal Sex-Dependent Differences in Mice After Mild Blast Traumatic Brain Injury
Proceedings of IMPRS · 2026
- Aldehyde dehydrogenase-2 modulates acrolein toxicity to promote neural repair after spinal cord injury
Neural Regeneration Research · 2026
- ALDH1a3 Protects Against Iron Overload−Induced Oxidative Stress and Mitochondrial Impairment in Renal Tubular Epithelial Cells
Antioxidants · 2026
- RETRACTED: Luo et al. Polyphyllin I Promotes Autophagic Cell Death and Apoptosis of Colon Cancer Cells via the ROS-Inhibited AKT/mTOR Pathway. Int. J. Mol. Sci. 2022, 23, 9368
International Journal of Molecular Sciences · 2025
- Reactive aldehyde species–mediated neuropathic pain in spinal cord injury: Mechanisms and therapeutic opportunities
Neural Regeneration Research · 2025
- Investigation the mechanism of iron overload-induced colonic inflammation following ferric citrate exposure
Ecotoxicology and Environmental Safety · 2024
- Progressive iron overload in middle-aged mice impairs olfactory function, triggers lipid oxidation and induces apoptosis
Frontiers in Pharmacology · 2024
- TRIM67 Implicates in Regulating the Homeostasis and Synaptic Development of Mitral Cells in the Olfactory Bulb
International Journal of Molecular Sciences · 2023
- A perspective on recent findings and future strategies for reactive aldehyde removal in spinal cord injury
Neural Regeneration Research · 2023
- RETRACTED: Polyphyllin I Promotes Autophagic Cell Death and Apoptosis of Colon Cancer Cells via the ROS-Inhibited AKT/mTOR Pathway
International Journal of Molecular Sciences · 2022
- Ferric citrate-induced colonic mucosal damage associated with oxidative stress, inflammation responses, apoptosis, and the changes of gut microbial composition
Ecotoxicology and Environmental Safety · 2022
- TRIM67 Deficiency Exacerbates Hypothalamic Inflammation and Fat Accumulation in Obese Mice
International Journal of Molecular Sciences · 2022
- Andrographolide inhibits murine embryonic neuronal development through PFKFB3-mediated glycolytic pathway
European Journal of Pharmacology · 2022
- Neural Regeneration Research×6
- bioRxiv (Cold Spring Harbor Laboratory)×5
- International Journal of Molecular Sciences×4
- Neuroscience×4
- Translational Neurodegeneration×3
- Jan M. Schwab
Medicine · The Ohio State University
- Lingxiao Deng
Medicine · Indiana University
- Phillip G. Popovich
Medicine · The Ohio State University
- Dana M. McTigue
Medicine · The Ohio State University
- D. Michele Basso
Medicine · The Ohio State University
This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.
Last updated Jul 20, 2026.
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