Ranjie Xu
Neuroscience · Purdue University West Lafayette
Publications
54
Citations
1,896
Est. group size
~16
Recurring co-author estimate
Active years
37
Publishing since 1990
Ranjie Xu's research uses human stem-cell-derived models—including brain organoids and human-animal brain chimeras—to study neurological conditions such as Alzheimer's disease, Down syndrome, and autism. A recurring focus is modeling microglia (the brain's immune cells) and neuroimmune interactions to understand how they contribute to neurodegeneration and neurodevelopmental disorders. Note that a few unrelated entries (crystal structure data, a poultry genetics study, and an image-editing AI paper) appear in the record but do not reflect the core research focus.
Publication output has been fairly steady over the past decade, averaging around 3-4 papers per year, with a peak in 2023 and some decline in the most recent two years.
Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026
- Patient-derived tau-seeded human neuronal chimeras recapitulate mature Alzheimer’s tau pathology and uncover human-specific neuronal vulnerability
bioRxiv (Cold Spring Harbor Laboratory) · 2026
- FLUX-Text: A Simple and Advanced Diffusion Transformer Baseline for Scene Text Editing
arXiv (Cornell University) · 2025
- Emerging Human Pluripotent Stem Cell-Based Human–Animal Brain Chimeras for Advancing Disease Modeling and Cell Therapy for Neurological Disorders
Neuroscience Bulletin · 2024
- Develop a vascularized neuroimmune organoid model for studying sporadic Alzheimer’s disease
Alzheimer s & Dementia · 2024
- CCDC 2234062: Experimental Crystal Structure Determination
The Cambridge Structural Database · 2023
- CCDC 2234063: Experimental Crystal Structure Determination
The Cambridge Structural Database · 2023
- CCDC 2234061: Experimental Crystal Structure Determination
The Cambridge Structural Database · 2023
- CCDC 2234060: Experimental Crystal Structure Determination
The Cambridge Structural Database · 2023
- Type-I-interferon signaling drives microglial dysfunction and senescence in human iPSC models of Down syndrome and Alzheimer’s disease
Cell stem cell · 2022
- Analyses of the autism-associated neuroligin-3 R451C mutation in human neurons reveal a gain-of-function synaptic mechanism
Molecular Psychiatry · 2022
- Developing human pluripotent stem cell-based cerebral organoids with a controllable microglia ratio for modeling brain development and pathology
Stem Cell Reports · 2021
- Type I Interferon Signaling Drives Microglial Dysfunction and Senescence in Human iPSC Models of Down Syndrome and Alzheimer's Disease
SSRN Electronic Journal · 2021
- Analyses of the Autism-associated Neuroligin-3 R451C Mutation in Human Neurons Reveals a Gain-of-Function Synaptic Mechanism
bioRxiv (Cold Spring Harbor Laboratory) · 2021
- Type I Interferon Signaling Drives Microglial Dysfunction and Senescence in Human iPSC Models of Down Syndrome and Alzheimer’s Disease
bioRxiv (Cold Spring Harbor Laboratory) · 2021
- Human iPSC-derived mature microglia retain their identity and functionally integrate in the chimeric mouse brain
Nature Communications · 2020
- bioRxiv (Cold Spring Harbor Laboratory)×9
- The Cambridge Structural Database×4
- Cell stem cell×3
- Molecular Psychiatry×3
- Stem Cell Reports×2
- Kaushik Sharma
Neuroscience · Purdue University West Lafayette
- Kyle Wettschurack
Neuroscience · Purdue University West Lafayette
- Priya Prakash
Neuroscience · Purdue University West Lafayette
- Kanchan Bisht
Neuroscience · Purdue University West Lafayette
- Colleen T. Harrington
Neuroscience · The Ohio State University
This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.
Last updated Jul 20, 2026.
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