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Rami A. Alfar

Biochemistry, Genetics and Molecular Biology · Purdue University West Lafayette

OpenAlex ORCID
Early career · publishing since 2020Rising activity
Cancer-related gene regulationEpigenetics and DNA MethylationMacrophage Migration Inhibitory FactorHistone Deacetylase Inhibitors ResearchImmune Cell Function and Interaction

Publications

21

Citations

83

Est. group size

~1

Recurring co-author estimate

Active years

7

Publishing since 2020

Research summary
AI-generated

Rami A. Alfar's work focuses on cancer immunology, particularly how immune cells within tumors—such as macrophages, myeloid-derived suppressor cells, and regulatory T cells—can be reprogrammed to improve the effectiveness of cancer immunotherapies. A recurring theme is the use of folate receptor beta and TLR7 agonists (compounds that stimulate innate immune responses) to enhance checkpoint inhibitor drugs used in cancer treatment. This research sits at the intersection of tumor biology, immunology, and drug development.

Tumor immunology and immune cell reprogrammingMacrophage and myeloid-derived suppressor cell biologyCheckpoint inhibitor immunotherapyFolate receptor beta as an immune targetTLR7 agonist drug development

Publication output was minimal or absent for most of the last decade, with a sharp concentration of activity in 2023 followed by sparse output in subsequent years, suggesting an irregular rather than steady publication pattern.

Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026

Publication cadence
Publications per year over the last 10 years — averaging 4.0/year recently
1718192020: 1 publication2021222023: 18 publications1823242025: 1 publication252026: 1 publication26
Recent publications
Publishes in
  • Cancer Research×2
  • Frontiers in Immunology×2
  • Journal of Medicinal Chemistry×1
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By research-topic overlap
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This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.

Last updated Jul 20, 2026.

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