Piotr Hadaczek
Biochemistry, Genetics and Molecular Biology · The Ohio State University
Publications
104
Citations
3,792
Est. group size
~4
Recurring co-author estimate
Active years
33
Publishing since 1993
Piotr Hadaczek's work focuses on gene therapy approaches for neurological diseases, particularly using engineered viral vectors (like AAV) to deliver therapeutic genes directly into the brain and spinal fluid. Their research spans preclinical studies in non-human primates for conditions such as Huntington's disease, Niemann-Pick disease, and Parkinson's disease, as well as drug delivery methods for pediatric brain tumors like diffuse intrinsic pontine glioma. Recent work also touches on CRISPR-based genome editing for cholesterol-related therapies.
Publication output was low and intermittent from 2017-2022, with a large but likely anomalous spike in 2023, followed by a return to modest activity in 2024-2025.
Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026
- Abstract 4140609: Engineering and Development of Optimal CRISPR Based Genome Modification Molecules for Safe and Effective LDL-C Lowering
Circulation · 2024
- Efficacy of convection enhanced delivery of MTX110 (soluble panobinostat) in preclinical Diffuse Intrinsic Pontine Glioma models using metabolic hyperpolarized 13C imaging
EJC Paediatric Oncology · 2023
- A traceless linker for aliphatic amines that rapidly and quantitatively fragments after reduction
Chemical Science · 2020
- Adeno-associated viral vector serotype 9–based gene therapy for Niemann-Pick disease type A
Science Translational Medicine · 2019
- DIPG-23. EFFICACY OF THE SOLUBLE PANOBINOSTAT (MTX110) IN PRECLINICAL DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG) MODELS
Neuro-Oncology · 2019
- Kinetics and MR-Based Monitoring of AAV9 Vector Delivery into Cerebrospinal Fluid of Nonhuman Primates
Molecular Therapy — Methods & Clinical Development · 2018
- Extensive Transduction and Enhanced Spread of a Modified AAV2 Capsid in the Non-human Primate CNS
Molecular Therapy · 2018
- Ganglioside Metabolism and Parkinson's Disease
Frontiers in Neuroscience · 2018
- MR-guided parenchymal delivery of adeno-associated viral vector serotype 5 in non-human primate brain
Gene Therapy · 2017
- Widespread AAV1- and AAV2-mediated transgene expression in the nonhuman primate brain: implications for Huntington's disease
Molecular Therapy — Methods & Clinical Development · 2016
- Validation of antibodies for neuroanatomical localization of the P2Y11 receptor in macaque brain
Journal of Chemical Neuroanatomy · 2016
- 621. Widespread Gene Delivery to the Nonhuman Primate Brain for the Treatment of Huntington's Disease
Molecular Therapy · 2016
- Molecular Therapy — Methods & Clinical Development×2
- Molecular Therapy×2
- Zenodo (CERN European Organization for Nuclear Research)×2
- Movement Disorders×1
- Gene Therapy×1
- Krystof S. Bankiewicz
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- Chelsea Bolyard
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- Lluı́s Samaranch
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- Kevin A. Cassady
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- Marxa L. Figueiredo
Biochemistry, Genetics and Molecular Biology · Purdue University West Lafayette
This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.
Last updated Jul 19, 2026.
Claim or correct this profile