Pedro De‐la‐Torre
Neuroscience · The Ohio State University
Publications
41
Citations
421
Est. group size
~8
Recurring co-author estimate
Active years
16
Publishing since 2011
Pedro De-la-Torre studies the molecular basis of hearing, focusing on proteins in the inner ear such as tip links, cadherin-23, protocadherin-15, TMC1, and PKHD1L1 that are essential for detecting sound and maintaining hair cell function. His work combines structural biology, computational simulations (molecular dynamics), and genetics to understand how mutations in these proteins cause hereditary hearing loss, and also explores small-molecule drug candidates that modulate ion channels involved in touch, temperature, and hearing-related sensory signaling.
Publication output has fluctuated over the last decade, with a dip around 2021-2022 followed by a renewed increase from 2023 through 2026, averaging about 3 publications per year over the last five years.
Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026
- BPS2026 – In silico hierarchical and calcium-dependent mechanics of inner-ear tip links under resting tension
Biophysical Journal · 2026
- The TASK-1 and TASK-3 activator JG-C3-98 attenuates cold and mechanical responses in primary somatosensory neurons
Frontiers in Pharmacology · 2026
- Data Sheet 1_The TASK-1 and TASK-3 activator JG-C3-98 attenuates cold and mechanical responses in primary somatosensory neurons.pdf
Figshare · 2026
- Identification of druggable binding sites and small molecules as modulators of TMC1
Communications Biology · 2025
- BPS2025 - Stretching tip links at the speed of sound: Coarse-grained simulations of a protein filament essential for hearing
Biophysical Journal · 2025
- BPS2025 - Stretching tip links at the speed of sound: Coarse-grained simulations of a protein filament essential for hearing
Biophysical Journal · 2025
- PKHD1L1 is required for stereocilia bundle maintenance, durable hearing function and resilience to noise exposure
Communications Biology · 2024
- PKHD1L1, a gene involved in the stereocilia coat, causes autosomal recessive nonsyndromic hearing loss
Human Genetics · 2024
- Identification of Druggable Binding Sites and Small Molecules as Modulators of TMC1
bioRxiv (Cold Spring Harbor Laboratory) · 2024
- PKHD1L1 is required for stereocilia bundle maintenance, durable hearing function and resilience to noise exposure
bioRxiv (Cold Spring Harbor Laboratory) · 2024
- <i>PKHD1L1</i> , A Gene Involved in the Stereocilia Coat, Causes Autosomal Recessive Nonsyndromic Hearing Loss
medRxiv · 2023
- Elastic properties of the inner-ear tip link explored using all-atom molecular dynamics simulations
Biophysical Journal · 2023
- 5-(Indol-2-yl)pyrazolo[3,4-b]pyridines as a New Family of TASK-3 Channel Blockers: A Pharmacophore-Based Regioselective Synthesis
Molecules · 2021
- Exploring the Structural Elements Responsible for Cis-Homodimerization of Inner Ear Cadherin-23
Biophysical Journal · 2020
- Zooming in on Cadherin-23: Structural Diversity and Potential Mechanisms of Inherited Deafness
Structure · 2018
- Biophysical Journal×12
- bioRxiv (Cold Spring Harbor Laboratory)×5
- Communications Biology×2
- Structure×1
- Computational Biology and Chemistry×1
- Wei-Hsiang Weng
Neuroscience · The Ohio State University
- Marcos M. Sotomayor
Neuroscience · The Ohio State University
- Sanket Walujkar
Neuroscience · The Ohio State University
- Eri Hashino
Neuroscience · Indiana University
- Amir M. Mafi
Neuroscience · The Ohio State University
This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.
Last updated Jul 19, 2026.
Claim or correct this profile