Publications
41
Citations
573
Est. group size
~1
Recurring co-author estimate
Active years
16
Publishing since 2011
Pathum M. Weerawarna's research sits at the intersection of medicinal chemistry, computational drug discovery, and enzyme mechanism studies. Their work includes designing chemical compounds that inhibit or inactivate specific proteins and enzymes (such as aminotransferases and viral proteases), synthesizing novel molecules, and developing machine-learning methods (graph neural networks) to predict how drug candidates bind to protein targets.
Publication activity was modest through 2018-2021, spiked sharply in 2023, and has continued at a steady pace since, averaging about 3.8 papers per year over the last five years.
Generated by claude-opus-4-8 from public bibliographic data · Jul 11, 2026
- Structure-Aware Compound-Protein Affinity Prediction via Graph Neural Network with Group Lasso Regularization
Computational and Structural Biotechnology Journal · 2026
- Structure-Aware Compound-Protein Affinity Prediction via Graph Neural Network with Group Lasso Regularization
Computational and Structural Biotechnology Journal · 2026
- Building Explainable Graph Neural Network by Sparse Learning for the Drug–Protein Binding Prediction
Journal of Computational Biology · 2025
- A Tetrahydrobiopterin-Displacing Potent Neuronal Nitric Oxide Synthase Inhibitor with an Unprecedented Binding Mode
ACS Medicinal Chemistry Letters · 2025
- Kinetically Controlled aza-Michael/Epimerization Cascade Enables a Scalable Total Synthesis of Putative (<i>+</i>)-Fumigaclavine F
Organic Letters · 2025
- How Polyproline Type II Conformation at P<sub>2</sub> Residues Influences the Success of Proline-Based Peptidyl Inhibitors Against Coronavirus Main Protease
Biochemistry · 2024
- Synthesis of (2<i>R</i>,4<i>S</i>)-4-Amino-5-hydroxybicyclo[3.1.1]heptane-2-carboxylic Acid via an Asymmetric Intramolecular Mannich Reaction
The Journal of Organic Chemistry · 2024
- Lyn Kinase Structure, Regulation, and Involvement in Neurodegenerative Diseases: A Mini Review
Kinases and Phosphatases · 2023
- Target Identification of a Class of Pyrazolone Protein Aggregation Inhibitor Therapeutics for Amyotrophic Lateral Sclerosis
ACS Central Science · 2023
- Main Proteases of Key RNA Viruses, Including Coronavirus, Recognize P2 Residues in the Polyproline Type II Conformation: Harnessing Proline's Unique Conformation for Protease Inhibitors
ChemRxiv · 2023
- Main Proteases of Key RNA Viruses Recognize P2 Residues in the Polyproline Type II Conformation: Harnessing Proline's Conformation with Protease Inhibitors
ChemRxiv · 2023
- Building explainable graph neural network by sparse learning for the drug-protein binding prediction
bioRxiv (Cold Spring Harbor Laboratory) · 2023
- Building explainable graph neural network by sparse learning for the drug-protein binding prediction
arXiv (Cornell University) · 2023
- Remarkable and Unexpected Mechanism for (<i>S</i>)-3-Amino-4-(difluoromethylenyl)cyclohex-1-ene-1-carboxylic Acid as a Selective Inactivator of Human Ornithine Aminotransferase
Journal of the American Chemical Society · 2021
- Theoretical and Mechanistic Validation of Global Kinetic Parameters of the Inactivation of GABA Aminotransferase by OV329 and CPP-115
ACS Chemical Biology · 2021
- Zenodo (CERN European Organization for Nuclear Research)×4
- Journal of the American Chemical Society×3
- European Journal of Medicinal Chemistry×2
- ACS Medicinal Chemistry Letters×2
- ChemRxiv×2
This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.
Last updated Jul 11, 2026.
Claim or correct this profile