Nitai Charan Giri

Biochemistry, Genetics and Molecular Biology · Indiana University

Epigenetics and DNA Methylation Metal-Catalyzed Oxygenation Mechanisms Crystallization and Solubility Studies X-ray Diffraction in Crystallography Metalloenzymes and iron-sulfur proteins

Publications

Citations

383

Est. group size

—

Recurring co-author estimate

Active years

Publishing since 2009

Research summary

AI-generated

Nitai Charan Giri studies the chemistry of enzymes and metal-containing proteins, using structural and spectroscopic methods to understand how these molecules carry out reactions in living systems. Recent work has examined vitamin biosynthesis (such as vitamin B6 and thiamin), how metal ions like nickel and iron affect enzyme function, and how metals can inhibit DNA-repair and gene-regulation enzymes. Additional publications cover applied topics such as drug delivery, biodegradable plastics, and water purification.

Metalloenzymes and iron-containing proteinsVitamin and cofactor biosynthesis (PLP, thiamin, vitamin B6)Metal ion effects on DNA repair and epigenetic enzymesStructural and spectroscopic characterization of enzyme intermediatesApplied biochemistry (drug delivery, biomaterials, water purification)

Publication activity has been steady at roughly one to two papers per year, with a modest increase around 2022.

Generated by claude-opus-4-8 from public bibliographic data · Jul 11, 2026

Publication cadence

Publications per year over the last 10 years — averaging 2.0/year recently

Recent publications

Oxidative Dearomatization of PLP in Thiamin Pyrimidine Biosynthesis in <i>Candida albicans</i>
Journal of the American Chemical Society · 2023
Anti-Cancer Activities of Natural Products
Advances in medical diagnosis, treatment, and care (AMDTC) book series · 2023
Protein and Peptide Drug Delivery
IntechOpen eBooks · 2022
Role of Transferrin in Iron Metabolism
Biochemistry · 2022
Development of Bioplastic and Biodegradable Plastics
Advances in human services and public health (AHSPH) book series · 2022
Polymers in Water Purification
Advances in environmental engineering and green technologies book series · 2022
Trapping and structural characterisation of a covalent intermediate in vitamin B <sub>6</sub> biosynthesis catalysed by the Pdx1 PLP synthase
RSC Chemical Biology · 2021
Nickel Ions Inhibit Histone Demethylase JMJD1A and DNA Repair Enzyme ABH2 by Replacing the Ferrous Iron in the Catalytic Centers
UNC Libraries · 2020
Structural Investigations Of Early IntremediatesAnd Nickel Inhibitions Complexes Of HumanDNA and Histone Demethylases
Scholarworks (University of Massachusetts Amherst) · 2019
Spectroscopy and DFT Calculations of Flavo–Diiron Nitric Oxide Reductase Identify Bridging Structures of NO-Coordinated Diiron Intermediates
ACS Catalysis · 2018
Spectroscopy and DFT Calculations of a Flavo-diiron Enzyme Implicate New Diiron Site Structures
Journal of the American Chemical Society · 2017
Nickel ions inhibit histone demethylase JMJD1A and DNA repair enzyme ABH2 by replacing the ferrous iron in the catalytic centers.
Journal of Biological Chemistry · 2017

Publishes in

Journal of the American Chemical Society×3
JBIC Journal of Biological Inorganic Chemistry×2
Journal of Biological Chemistry×2
ACS Catalysis×1
IntechOpen eBooks×1

This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.

Last updated Jul 11, 2026.

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