LabCompass

Nicholas Noinaj

Biochemistry, Genetics and Molecular Biology · Purdue University West Lafayette

OpenAlex ORCID
Mid career · publishing since 2008
Bacterial Genetics and BiotechnologyRNA and protein synthesis mechanismsBacterial Infections and VaccinesAntibiotic Resistance in BacteriaEnzyme Structure and Function

Publications

156

Citations

6,679

Est. group size

~5

Recurring co-author estimate

Active years

19

Publishing since 2008

Research summary
AI-generated

Nicholas Noinaj's research focuses on understanding how bacteria build and maintain their outer membranes, particularly the protein machinery that inserts and assembles proteins into these membranes in species like Neisseria and Fusobacterium, which are relevant to infectious disease. A related line of work involves studying enzymes called protein methyltransferases and designing small-molecule inhibitors that could serve as starting points for future drugs. The lab uses structural biology methods, such as X-ray crystallography, to visualize these proteins and their mechanisms in detail.

Bacterial outer membrane protein assemblyStructural biology of membrane proteinsNeisseria and Fusobacterium pathogen biologyProtein methyltransferase enzymes and inhibitor designMetal (zinc) acquisition and nutritional immunity in bacteria

Publication output was fairly steady at around 9-13 papers per year from 2017 to 2021, but has declined and become more variable since 2022, with notably lower counts in 2023-2024 before an uptick in 2025.

Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026

Publication cadence
Publications per year over the last 10 years — averaging 5.6/year recently
2017: 9 publications172018: 9 publications182019: 12 publications192020: 12 publications202021: 13 publications13212022: 9 publications222023: 8 publications232024: 2 publications242025: 7 publications252026: 2 publications26
Recent publications
Publishes in
  • Acta Crystallographica Section A Foundations and Advances×13
  • Journal of Medicinal Chemistry×9
  • Biophysical Journal×7
  • Nature×4
  • Structure×4
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This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.

Last updated Jul 20, 2026.

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