Mounika Goruganthu
Biochemistry, Genetics and Molecular Biology · The Ohio State University
Publications
12
Citations
191
Est. group size
~26
Recurring co-author estimate
Active years
8
Publishing since 2019
Mounika Goruganthu studies how immune cells, particularly a type called myeloid-derived suppressor cells, help tumors evade the immune system and resist chemotherapy. Recent work focuses on cellular energy production (mitochondrial function) and a specific protein transporter (Exportin 1/XPO1) as ways to control these suppressive immune cells in cancer. This research sits at the intersection of cancer biology and immunology, aiming to identify targets that could make cancer treatments more effective.
Publication output was minimal or absent in the earlier part of the decade but has increased modestly in recent years, with the highest output occurring in 2024-2025.
Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026
- Myeloid-derived suppressor cell mitochondrial fitness governs chemotherapeutic efficacy in hematologic malignancies
Nature Communications · 2024
- Exportin 1 governs the immunosuppressive functions of myeloid-derived suppressor cells in tumors through ERK1/2 nuclear export
Cellular and Molecular Immunology · 2024
- Exportin 1 (XPO1) blockade regulates immunosuppressive function of tumor myeloid derived suppressor cells
The Journal of Immunology · 2024
- Cancer Research×3
- Journal for ImmunoTherapy of Cancer×2
- Nature Communications×1
- JNCI Journal of the National Cancer Institute×1
- Frontiers in Immunology×1
- YunZhou Liu
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- Benjamin M. Johnson
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- Andrea R. Merchak
Biochemistry, Genetics and Molecular Biology · Indiana University
- Amna Bibi
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- Amy R. Mackos
Biochemistry, Genetics and Molecular Biology · The Ohio State University
This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.
Last updated Jul 19, 2026.
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