LabCompass

Megan C. Thielges

Physics and Astronomy · Indiana University

OpenAlex ORCID
Spectroscopy and Quantum Chemical StudiesProtein Structure and DynamicsPhotosynthetic Processes and MechanismsMass Spectrometry Techniques and ApplicationsHemoglobin structure and function

Publications

74

Citations

2,172

Est. group size

—

Recurring co-author estimate

Active years

21

Publishing since 2005

Research summary
AI-generated

Megan C. Thielges studies how proteins move and change shape while they carry out their functions, using advanced light-based techniques—especially two-dimensional infrared (2D IR) spectroscopy—to observe these dynamics in fine detail. Her group develops chemical labels and spectroscopic methods to probe specific sites within proteins, including enzymes involved in electron transfer and reactions like those of cytochrome P450 and nitric oxide synthase. The work bridges physical chemistry, spectroscopy, and biochemistry to understand the link between molecular motion and biological activity.

Protein dynamics and conformational changesTwo-dimensional infrared (2D IR) spectroscopyVibrational probes and site-specific labelingRedox and metalloprotein enzymesElectron transfer mechanisms

Publication activity has been relatively steady but modest, with a slight slowing to about 2-3 papers per year in the most recent years compared to earlier in the decade.

Generated by claude-opus-4-8 from public bibliographic data · Jul 11, 2026

Publication cadence
Publications per year over the last 10 years — averaging 2.4/year recently
2017: 6 publications6172018: 5 publications182019: 4 publications192020: 3 publications202021: 6 publications6212022: 5 publications222023: 2 publications232024: 3 publications242025: 2 publications2526
Recent publications
Publishes in
  • The Journal of Physical Chemistry B×4
  • Analytical Chemistry×4
  • Physical Chemistry Chemical Physics×3
  • Biochemistry×3
  • Journal of the American Chemical Society×3

This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.

Last updated Jul 11, 2026.

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