Manjula Karpurapu
Immunology and Microbiology · The Ohio State University
Publications
65
Citations
1,676
Est. group size
~6
Recurring co-author estimate
Active years
28
Publishing since 1999
Manjula Karpurapu studies how the lungs become inflamed and how that inflammation is resolved, focusing on conditions such as acute lung injury, asthma, and pulmonary fibrosis. A recurring theme is the role of macrophages (a type of immune cell) and tiny cell-released particles called extracellular vesicles, which carry proteins, lipids, and genetic material that influence inflammation and tissue repair in the lungs. This work combines molecular immunology, lipid biology, and mitochondrial biology to understand and potentially treat lung disease.
Publication output has been relatively steady over the past decade with year-to-year fluctuations, showing a modest uptick in the most recent years (2024-2026) after a quieter period around 2018-2021.
Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026
- Extracellular Vesicle Lipid Cargo Orchestrates Lung Inflammation and Resolution
American Journal of Respiratory Cell and Molecular Biology · 2026
- Hdac11 promotes idiopathic pulmonary fibrosis through macrophage M2-type polarization and myofibroblast accumulation by inhibiting Parkin-dependent mitophagy
Nature Communications · 2026
- Disease-dependent airway epithelial responses to acute electronic cigarette aerosol exposure: a pilot single-cell analysis
Toxicological Sciences · 2026
- Specialized Pro-Resolving Mediator loaded Extracellular Vesicles Mitigate Pulmonary Inflammation
bioRxiv (Cold Spring Harbor Laboratory) · 2025
- Myeloid-specific TFAM deficiency drives mitochondrial DNA stress and exacerbates allergic airway inflammation
bioRxiv (Cold Spring Harbor Laboratory) · 2025
- Specialized Pro-resolution Mediator Loaded Extracellular Vesicles Mitigate LPS-induced Acute Lung Injury in Mice
American Journal of Respiratory and Critical Care Medicine · 2025
- Specialized proresolving mediator-loaded extracellular vesicles mitigate pulmonary inflammation
American Journal of Respiratory Cell and Molecular Biology · 2025
- DNMT1 mRNA transfer via macrophage-derived extracellular vesicles following LPS exposure regulates TNFα gene methylation
Shock · 2025
- The calcineurin–NFATc pathway modulates the lipid mediators in BAL fluid extracellular vesicles, thereby regulating microvascular endothelial cell barrier function
Frontiers in Physiology · 2024
- Epigallocatechin gallate regulates the myeloid-specific transcription factor PU.1 in macrophages
PLoS ONE · 2024
- Genetic Ablation of TFAM in Alveolar Macrophages Exacerbates Allergic Airway Inflammation
2024
- NFATc3 Promotes Pulmonary Inflammation and Fibrosis by Regulating Production of CCL2 and CXCL2 in Macrophage.
PubMed · 2023
- NFATc3 Promotes Pulmonary Inflammation and Fibrosis by Regulating Production of CCL2 and CXCL2 in Macrophages
Aging and Disease · 2022
- Lipidomic Profiling of Bronchoalveolar Lavage Fluid Extracellular Vesicles Indicates Their Involvement in Lipopolysaccharide-Induced Acute Lung Injury
Journal of Innate Immunity · 2022
- Supplementary Material for: Lipidomic Profiling of Bronchoalveolar Lavage Fluid Extracellular Vesicles Indicates Their Involvement in Lipopolysaccharide-Induced Acute Lung Injury
Figshare · 2022
- American Journal of Respiratory Cell and Molecular Biology×3
- Oncotarget×2
- Journal of Innate Immunity×2
- American Journal of Physiology-Lung Cellular and Molecular Physiology×2
- Shock×2
- Jordan Moore
Immunology and Microbiology · The Ohio State University
- Alexander Abreo
Immunology and Microbiology · The Ohio State University
- Andrew Stiff
Immunology and Microbiology · The Ohio State University
- Anthony Cannon
Immunology and Microbiology · Indiana University
- Carter Allen
Immunology and Microbiology · The Ohio State University
This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.
Last updated Jul 19, 2026.
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