Malcolm E. Winkler
Biochemistry, Genetics and Molecular Biology · Indiana University
Publications
180
Citations
11,104
Est. group size
—
Recurring co-author estimate
Active years
49
Publishing since 1978
Malcolm E. Winkler studies the molecular biology of the bacterium Streptococcus pneumoniae (pneumococcus), a major cause of pneumonia and other infections. The research focuses on how these bacteria build and repair their cell walls, divide, and cause disease, including how they resist antibiotics like penicillin and amoxicillin. Much of the work combines genetics, biochemistry, and imaging to understand essential proteins involved in bacterial cell division.
Publication activity has been fairly steady over the past decade, averaging around five papers per year with occasional higher-output years such as 2019 and 2024.
Generated by claude-opus-4-8 from public bibliographic data · Jul 11, 2026
- Uncovering the Biological Function of the Peptidoglycan Hydrolase PcsB in Streptococcus pneumoniae
bioRxiv (Cold Spring Harbor Laboratory) · 2025
- A bacterial cell wall repair and modification system to resist host antibacterial factors
bioRxiv (Cold Spring Harbor Laboratory) · 2024
- Editor's evaluation: Amoxicillin-resistant Streptococcus pneumoniae can be resensitized by targeting the mevalonate pathway as indicated by sCRilecs-seq
2022
- Cellular Mn/Zn Ratio Influences Phosphoglucomutase Activity and Capsule Production in Streptococcus pneumoniae D39
Journal of Bacteriology · 2021
- Pivotal Roles for Ribonucleases in Streptococcus pneumoniae Pathogenesis
mBio · 2021
- Treadmilling FtsZ polymers drive the directional movement of sPG-synthesis enzymes via a Brownian ratchet mechanism
Nature Communications · 2021
- Undermodification cues division
Nature Chemical Biology · 2021
- Pivotal Roles for Ribonucleases in <i>Streptococcus pneumoniae</i> Pathogenesis
bioRxiv (Cold Spring Harbor Laboratory) · 2021
- The Pneumococcal Divisome: Dynamic Control of Streptococcus pneumoniae Cell Division
Frontiers in Microbiology · 2021
- Chemical tools for selective activity profiling of bacterial penicillin-binding proteins
Methods in enzymology on CD-ROM/Methods in enzymology · 2020
- Bacterial Pathogenesis: A Molecular Approach, Fourth Edition
2019
- Competence beyond Genes: Filling in the Details of the Pneumococcal Competence Transcriptome by a Systems Approach
Journal of Bacteriology · 2019
- Treadmilling FtsZ polymers drive the directional movement of sPG-synthesis enzymes <i>via</i> a Brownian ratchet mechanism
bioRxiv (Cold Spring Harbor Laboratory) · 2019
- Novel Electrophilic Scaffold for Imaging of Essential Penicillin-Binding Proteins in <i>Streptococcus pneumoniae</i>
ACS Chemical Biology · 2017
- Roles of the Essential Protein FtsA in Cell Growth and Division in Streptococcus pneumoniae
Journal of Bacteriology · 2016
- bioRxiv (Cold Spring Harbor Laboratory)×16
- Molecular Microbiology×9
- Journal of Bacteriology×7
- Nature Communications×4
- Proceedings of the National Academy of Sciences×3
This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.
Last updated Jul 11, 2026.
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