Majid Kazemian
Immunology and Microbiology · Purdue University West Lafayette
Publications
150
Citations
3,512
Est. group size
~27
Recurring co-author estimate
Active years
22
Publishing since 2005
Majid Kazemian's research focuses on how immune cells, especially T cells and complement system proteins, are regulated at the level of gene expression and how this regulation contributes to diseases such as cancer, kidney fibrosis, autoimmunity, and viral infection. A recurring theme is the 'intrinsic' complement system—complement proteins acting inside cells rather than in blood—and how transcription factors and gene-regulatory elements shape immune cell identity and function. The lab combines molecular immunology with genomics-style approaches to study gene regulation in immune and epithelial cells.
Publication output has grown substantially over the past decade, rising from just a couple of papers per year in 2017 to a sustained pace of roughly 15 papers per year in recent years.
Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026
- Peptide-mediated modulation of complement-like CD109 boosts T cell anti-tumor responses 2967
The Journal of Immunology · 2025
- Inflammatory cytokines drive local C3 transcription to regulate metabolic reprogramming in kidney epithelial cells and subsequent fibrosis
Immunobiology · 2025
- A ‘sweet spot’ for complement receptor CD46 activity: CYT-1 regulates glycolytic and moonlighting functions of glycolytic enzymes during human CD4+ T cell activation
Immunobiology · 2025
- Publisher Correction: Critical functions for STAT5 tetramers in the maturation and survival of natural killer cells
Nature Communications · 2025
- Kaposi’s sarcoma herpesvirus latency-associated nuclear antigen broadly regulates viral gene expression and is essential for lytic infection
PLoS Pathogens · 2024
- Cell-Intrinsic C3 and Complement Factor B from Proximal Tubular Epithelial Cells Drive Post-Injury Kidney Fibrosis
Journal of the American Society of Nephrology · 2024
- Nuclear-Localized Complement Factor B (CFB) Is a DNA-Binding Enzyme Regulating Histone Degradation
Journal of the American Society of Nephrology · 2024
- The CD4 T cell-intrinsic C3-like molecule CD109 prevents hyper-inflammatory T cell responses
The Journal of Immunology · 2024
- The role of transcription factors in shaping regulatory T cell identity
Nature reviews. Immunology · 2023
- Distinct use of super-enhancer elements controls cell type–specific CD25 transcription and function
Science Immunology · 2023
- Cell-autonomous complement C3 maintains prostate epithelial cell homeostasis and prevents malignant transformation
The Journal of Immunology · 2023
- EBV-associated diseases: Current therapeutics and emerging technologies
Frontiers in Immunology · 2022
- Non-coding RNAs in immunoregulation and autoimmunity: Technological advances and critical limitations
Journal of Autoimmunity · 2022
- Investigation of the causal etiology in a patient with T-B+NK+ immunodeficiency
Frontiers in Immunology · 2022
- A Noncoding Germline Variant Creates a Gain-of-Function <i>De Novo</i> Enhancer That up-Regulates <i>IL5</i> Transcription to Cause Familial Hypereosinophilia, Revealing a Previously Undescribed Mechanism for Human Disease
Blood · 2022
- The Journal of Immunology×23
- bioRxiv (Cold Spring Harbor Laboratory)×13
- Science Immunology×5
- Frontiers in Immunology×5
- Immunobiology×5
- Chang H. Kim
Immunology and Microbiology · Purdue University West Lafayette
- Devin M. Jones
Immunology and Microbiology · The Ohio State University
- Alexander L. Dent
Immunology and Microbiology · Indiana University
- Can Li
Immunology and Microbiology · Purdue University West Lafayette
- Ephraim Ansa-Addo
Immunology and Microbiology · The Ohio State University
This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.
Last updated Jul 20, 2026.
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