Lynda F. Bonewald
Biochemistry, Genetics and Molecular Biology · Indiana University
Publications
469
Citations
40,713
Est. group size
~5
Recurring co-author estimate
Active years
50
Publishing since 1977
Lynda F. Bonewald studies bone biology, focusing on osteocytes e2 the cells embedded within bone that act as regulators of skeletal health. A central theme of her work is how muscle and bone communicate through secreted molecules (such as irisin and the metabolite L-BAIBA), and how exercise, aging, and mechanical loading affect the musculoskeletal system. Her research combines animal models with analytical chemistry methods like mass spectrometry to measure biological signaling molecules.
Publication activity has fluctuated over the past decade, with a peak around 2019 and 2023 but generally lower output in the most recent years, averaging about 10 per year over the last five years.
Generated by claude-opus-4-8 from public bibliographic data · Jul 11, 2026
- Sex specific effects of irisin on the skeleton
Bone Research · 2026
- Separation and Quantification of Isomeric Forms of Aminobutyric Acids
Methods in molecular biology · 2025
- L-β-aminoisobutyric acid (L-BAIBA) in combination with voluntary wheel running exercise enhances musculoskeletal properties in middle-age male mice
Aging · 2025
- Force-Loaded Cementocytes Regulate Osteoclastogenesis via S1P/S1PR1/Rac1 Axis
Journal of Dental Research · 2023
- Irisin Enhances Mitochondrial Function in Osteoclast Progenitors during Differentiation
Biomedicines · 2023
- Muscle secreted factors enhance activation of the PI3K/Akt and β-catenin pathways in murine osteocytes
Bone · 2023
- Mass Spectrometry Approaches for Detection and Determination of Prostaglandins from Biological Samples
Methods in molecular biology · 2023
- Quantification of Endocannabinoids from Biological Samples Using Liquid Chromatography–Tandem Mass Spectrometry
Methods in molecular biology · 2023
- Advanced Methodology for Rapid Isolation of Single Myofibers from Flexor Digitorum Brevis Muscle
Tissue Engineering Part C Methods · 2023
- The Skeleton as a Secretory Organ
Calcified Tissue International · 2023
- The new endocrinology of osteocytes
Endocrine Abstracts · 2023
- Role of the Osteocyte in Musculoskeletal Disease
Current Osteoporosis Reports · 2023
- Potential influences on optimizing long-term musculoskeletal health in children and adolescents with X-linked hypophosphatemia (XLH)
Orphanet Journal of Rare Diseases · 2022
- Canonical Wnt/β‐catenin signaling has positive effects on osteogenesis, but can have negative effects on cementogenesis
Journal of Periodontology · 2022
- Body weight influences musculoskeletal adaptation to long-term voluntary wheel running during aging in female mice
Aging · 2022
- Elsevier eBooks×9
- PMC×9
- Journal of Bone and Mineral Research×7
- JBMR Plus×6
- Bone×4
This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.
Last updated Jul 11, 2026.
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