Lorena Rosas
Biochemistry, Genetics and Molecular Biology · The Ohio State University
Publications
43
Citations
401
Est. group size
~13
Recurring co-author estimate
Active years
8
Publishing since 2019
Lorena Rosas studies how lung cells age and become dysfunctional, with a particular focus on cellular senescence (a state where cells stop dividing but remain metabolically active and can promote tissue damage) and its role in lung diseases such as idiopathic pulmonary fibrosis and influenza-related lung injury. Her work combines single-cell and spatial transcriptomics (methods for measuring gene activity in individual cells and mapping it to tissue location), computational tools, and mass spectrometry imaging to characterize aging and diseased lung tissue at high resolution. This research aims to identify molecular signatures of senescent and disease-associated cells that could inform future treatments for chronic lung conditions.
Publication output was minimal before 2022 but rose sharply starting in 2023, suggesting a recent and substantial increase in research activity over the past few years.
Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026
- SenSet defines cell-type specific senescence signatures in the aged human lung
The EMBO Journal · 2026
- Advancing biological understanding of cellular senescence with computational multiomics
Nature Genetics · 2025
- BIK polymorphism and proteasome regulation unveil host risk factor for severe influenza
Proceedings of the National Academy of Sciences · 2025
- Light-Reactive Norharmane Derivatization of Lipid Isomers by Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry
Analytical Chemistry · 2025
- Modulation of an aberrant basal cell program in human alveolar epithelial spheroids and lung slices
Respiratory Research · 2025
- Development of ARDS in Influenza A Virus-infected Mice is ATII Cell Mitochondria-dependent
American Journal of Respiratory and Critical Care Medicine · 2025
- Impact of Common Co-morbidities on Cardiopulmonary Function and Alveolar Fluid Clearance in Mice
American Journal of Respiratory and Critical Care Medicine · 2025
- Characterizing Cellular Heterogeneity and Transcriptomic Features of Senotype Using Deep Graph Representation Learning
bioRxiv (Cold Spring Harbor Laboratory) · 2025
- Single Cell − RNA Sequencing FFPE Heart Tissue Using Fixed RNA Profiling v1
2025
- Single Cell MALDI-MSI Analysis of Lipids and Proteins within a Replicative Senescence Fibroblast Model
Journal of the American Society for Mass Spectrometry · 2024
- FOXK2 targeting by the SCF-E3 ligase subunit FBXO24 for ubiquitin mediated degradation modulates mitochondrial respiration
Journal of Biological Chemistry · 2024
- Peroxisome Proliferator-Activated Receptor Alpha Stimulation Preserves Renal Tight Junction Components in a Rat Model of Early-Stage Diabetic Nephropathy
International Journal of Molecular Sciences · 2024
- scDOT: optimal transport for mapping senescent cells in spatial transcriptomics
Genome biology · 2024
- Recovering single-cell expression profiles from spatial transcriptomics with scResolve
Cell Reports Methods · 2024
- The Fourth Annual Symposium of the Midwest Aging Consortium
The Journals of Gerontology Series A · 2024
- bioRxiv (Cold Spring Harbor Laboratory)×8
- Respiratory Research×2
- The Journals of Gerontology Series A×2
- American Journal of Respiratory and Critical Care Medicine×2
- Nature Aging×1
- Austin Hartman
Biochemistry, Genetics and Molecular Biology · Purdue University West Lafayette
- Andreas Bueckle
Biochemistry, Genetics and Molecular Biology · Indiana University
- Anjun Ma
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- Andrew J. C. Russell
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- Bruce W. Herr
Biochemistry, Genetics and Molecular Biology · Indiana University
This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.
Last updated Jul 19, 2026.
Claim or correct this profile