LabCompass

Lindsey D. Mayo

Medicine · Indiana University

OpenAlex ORCID
Cancer-related Molecular PathwaysCancer Research and TreatmentsCancer, Hypoxia, and MetabolismCell death mechanisms and regulationUbiquitin and proteasome pathways

Publications

134

Citations

7,937

Est. group size

—

Recurring co-author estimate

Active years

31

Publishing since 1996

Research summary
AI-generated

Lindsey D. Mayo studies the molecular signaling pathways that control cancer, with a focus on the proteins Mdm2 and p53 that regulate cell survival, growth, and tumor suppression. The research examines how chemical modifications to these proteins (such as phosphorylation and neddylation) influence their activity and how disruptions can drive cancers like breast cancer, osteosarcoma (a bone cancer), and endometrial tumors. This work aims to clarify the biochemical mechanisms that determine whether cells become cancerous.

Mdm2 and p53 tumor-suppressor signalingRegulation of proteins by phosphorylation and neddylationCancer cell death and survival mechanismsMolecular pathways in specific cancers (breast, bone, endometrial)Ubiquitin/proteasome protein-degradation pathways

Publication activity has been variable, with a notable spike in 2023 followed by lower counts in recent years, averaging about seven publications per year over the last five years.

Generated by claude-opus-4-8 from public bibliographic data · Jul 11, 2026

Publication cadence
Publications per year over the last 10 years — averaging 7.0/year recently
2017: 6 publications172018: 9 publications182019: 4 publications192020: 5 publications20212022: 1 publication222023: 27 publications27232024: 4 publications242025: 1 publication252026: 2 publications26
Recent publications
Publishes in
  • PMC×4
  • Author eBooks×3
  • Cancer Research×3
  • Nature Communications×2
  • Science Signaling×2

This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.

Last updated Jul 11, 2026.

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