Li‐Chun Tu
Biochemistry, Genetics and Molecular Biology · The Ohio State University
Publications
39
Citations
1,466
Est. group size
~3
Recurring co-author estimate
Active years
23
Publishing since 2004
Li-Chun Tu's research develops tools that combine CRISPR-based genome targeting with advanced imaging (like super-resolution microscopy) to visualize and manipulate how DNA and proteins are organized inside living cells. This work touches on chromatin structure, nuclear architecture, and engineering new molecular tags and platforms for studying gene regulation in real time. The lab also explores applications ranging from yeast gene control to identifying natural products from genomic data.
Publication output was higher around 2017-2018, dipped to zero in 2020-2021, and has since resumed at a modest, fairly steady pace of a few papers per year.
Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026
- BPS2026 – CRISPR-CLIP: A novel programmable platform for engineering chromatin organization in live cells
Biophysical Journal · 2026
- Ligand-Induced Self-Complementing Tag (LiSC-Tag) as an Epitope Tag for Live-Cell Super-Resolution Imaging and Functional Manipulation of Cellular Proteins
Journal of the American Chemical Society · 2025
- Functional analysis of <i>Saccharomyces cerevisiae FLO</i> genes through optogenetic control
FEMS Yeast Research · 2025
- Genome-Based Mining of Carpatamides I–M and Their Candidate Biosynthetic Gene Cluster
Marine Drugs · 2024
- C-BERST: defining subnuclear proteomic landscapes at genomic elements with dCas9–APEX2
Nature Methods · 2018
- Mapping subnuclear proteomes onto genome architecture via C-BERST
Protocol Exchange · 2018
- Investigating molecular crowding within nuclear pores using polarization-PALM
eLife · 2017
- C-BERST: Defining subnuclear proteomic landscapes at genomic elements with dCas9-APEX2
bioRxiv (Cold Spring Harbor Laboratory) · 2017
- Author response: Investigating molecular crowding within nuclear pores using polarization-PALM
2017
- Multiplexed labeling of genomic loci with dCas9 and engineered sgRNAs using CRISPRainbow
Nature Biotechnology · 2016
- CRISPR-Cas9 nuclear dynamics and target recognition in living cells
The Journal of Cell Biology · 2016
- Interrogation of CRISPR Dynamics with Fluorescent Single Guide RNAs in Live Cells
Biophysical Journal · 2016
- bioRxiv (Cold Spring Harbor Laboratory)×6
- Biophysical Journal×5
- The Journal of Cell Biology×2
- Nature Methods×2
- Nature Biotechnology×1
- Yu-Chieh Chung
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- Yuichiro Takagi
Biochemistry, Genetics and Molecular Biology · Indiana University
- Robin P. Wharton
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- René M. Arvola
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- Whitney R. Smith-Kinnaman
Biochemistry, Genetics and Molecular Biology · Indiana University
This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.
Last updated Jul 19, 2026.
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