LabCompass

Lauren O. Bakaletz

Immunology and Microbiology · The Ohio State University

OpenAlex ORCID
Established · publishing since 1985
Bacterial Infections and VaccinesPneumonia and Respiratory InfectionsEar Surgery and Otitis MediaRespiratory viral infections researchAntimicrobial Peptides and Activities

Publications

241

Citations

10,210

Est. group size

~3

Recurring co-author estimate

Active years

42

Publishing since 1985

Research summary
AI-generated

Lauren O. Bakaletz's research focuses on bacterial biofilms, particularly those formed by nontypeable Haemophilus influenzae and related respiratory pathogens, and how these biofilms contribute to chronic and recurrent infections such as otitis media (middle ear infections) and chronic respiratory conditions like COPD and chronic rhinosinusitis. Her work investigates molecular mechanisms bacteria use to persist and evade treatment (such as phase variation, adhesins, and extracellular DNA-based biofilm matrices), and develops potential therapies including monoclonal antibodies and vaccine antigens aimed at disrupting biofilms and enhancing antibiotic effectiveness.

Bacterial biofilms and antibiotic resistanceNontypeable Haemophilus influenzae pathogenesisOtitis media and chronic respiratory infectionsMonoclonal antibody and vaccine developmentBacterial adhesion and phase variation mechanisms

Publication output has gradually declined from about 9-12 papers per year in 2017-2020 to roughly 5 per year on average over the last five years, though a rebound occurred in 2025.

Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026

Publication cadence
Publications per year over the last 10 years — averaging 5.0/year recently
2017: 9 publications172018: 12 publications12182019: 9 publications192020: 9 publications202021: 6 publications212022: 6 publications222023: 5 publications232024: 3 publications242025: 8 publications252026: 3 publications26
Recent publications
Publishes in
  • The Laryngoscope×5
  • Frontiers in Microbiology×5
  • mBio×5
  • EBioMedicine×4
  • npj Biofilms and Microbiomes×4
Similar researchers
By research-topic overlap

This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.

Last updated Jul 19, 2026.

Claim or correct this profile