Kye Stachowski
Biochemistry, Genetics and Molecular Biology · The Ohio State University
Publications
16
Citations
176
Est. group size
~3
Recurring co-author estimate
Active years
10
Publishing since 2016
Kye Stachowski's research uses structural biology techniques, especially cryo-electron microscopy (cryo-EM), to understand how proteins involved in gene regulation and DNA processing work at the molecular level. Their studies examine proteins like Cre recombinase (used in genetic engineering), zinc finger proteins that control gene activity, and tumor suppressor proteins, focusing on how these molecules change shape to perform their functions. Recent work also includes developing automated methods for cryo-EM data processing.
Publication output has been steady over the last five years, averaging under two papers annually with consistent activity from 2020 through 2025 after a gap in the prior years.
Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026
- Conformational dynamics in specialized <scp>C<sub>2</sub>H<sub>2</sub></scp> zinc finger domains enable zinc‐responsive gene repression in <i>S. pombe</i>
Protein Science · 2025
- End-to-end automation of repeat-target cryo-EM structure determination in CryoSPARC
bioRxiv (Cold Spring Harbor Laboratory) · 2025
- Automated Cryo-EM Processing of GPCRs in CryoSPARC
Structural Dynamics · 2025
- Structural basis of nearest-neighbor cooperativity in the ring-shaped gene regulatory protein TRAP from protein engineering and cryo-EM
Proceedings of the National Academy of Sciences · 2024
- Structural basis of nearest-neighbor cooperativity in the ring-shaped gene regulatory protein TRAP from protein engineering and cryo-EM
bioRxiv (Cold Spring Harbor Laboratory) · 2024
- Conformational dynamics in specialized C <sub>2</sub> H <sub>2</sub> zinc finger domains enable zinc-responsive gene repression in S. pombe
bioRxiv (Cold Spring Harbor Laboratory) · 2024
- Merlin tumor suppressor function is regulated by PIP2-mediated dimerization
PLoS ONE · 2023
- Mechanisms of Cre recombinase synaptic complex assembly and activation illuminated by Cryo-EM
Nucleic Acids Research · 2022
- Un <i>lox</i> ing the assembly and activation mechanism of Cre recombinase using Cryo-EM
bioRxiv (Cold Spring Harbor Laboratory) · 2021
- Merlin Tumor Suppressor Function is Regulated by PIP <sub>2</sub> -Mediated Dimerization
bioRxiv (Cold Spring Harbor Laboratory) · 2021
- Unloxing the assembly and activation mechanism of Cre recombinase using cryo-EM
Acta Crystallographica Section A Foundations and Advances · 2021
- Rational design of cell-permeable cyclic peptides containing a d-Pro-l-Pro motif
Bioorganic & Medicinal Chemistry · 2020
- DNA binding induces a <i>cis</i> -to- <i>trans</i> switch in Cre recombinase to enable intasome assembly
Proceedings of the National Academy of Sciences · 2020
- DNA Binding Induces a <i>cis</i> to <i>trans</i> Switch in Cre Recombinase to Enable Intasome Assembly
bioRxiv (Cold Spring Harbor Laboratory) · 2020
- Abscisic acid controlled sex before transpiration in vascular plants
Proceedings of the National Academy of Sciences · 2016
- bioRxiv (Cold Spring Harbor Laboratory)×6
- Proceedings of the National Academy of Sciences×3
- Nucleic Acids Research×2
- Bioorganic & Medicinal Chemistry×1
- Protein Science×1
- Hong Li
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- Tammy J. Bullwinkle
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- Eric Danhart
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- Crystal E. Love
Biochemistry, Genetics and Molecular Biology · Indiana University
- Bing Wang
Biochemistry, Genetics and Molecular Biology · The Ohio State University
This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.
Last updated Jul 19, 2026.
Claim or correct this profile