Kristi DeBoeuf
Biochemistry, Genetics and Molecular Biology · Indiana University
Publications
16
Citations
7
Est. group size
—
Recurring co-author estimate
Active years
13
Publishing since 2014
Kristi DeBoeuf studies how proteins linked to Alzheimer's disease, particularly amyloid beta peptides, affect electrical signaling in nerve cells. Much of the work focuses on how these peptides suppress or alter the activity of ion channels (Kv1.1 and Kv1.2, which control the flow of potassium ions) and nicotine-sensitive receptors, and the internal cell-signaling steps (involving calcium and enzymes called kinases) that drive these effects. The research uses laboratory model systems such as frog (Xenopus) egg cells to examine channel and receptor behavior.
Publication activity has been steady but modest over the last decade, averaging about one paper per year in recent years with an early peak around 2018-2019.
Generated by claude-opus-4-8 from public bibliographic data · Jul 11, 2026
- BPS2026 - Amyloid β suppression of Kv1.2 channels involves PYK2-dependent modulation of Y132
Biophysical Journal · 2026
- The role of Y132‐ in Tyrosine‐Kinase dependent suppression of homomeric Kv1.2: Implications for Alzheimer's Disease
Alzheimer s & Dementia · 2025
- Calcium‐ and Tyrosine Kinase‐Dependent Suppression of Macroscopic Homomeric Kv1.2 and Heteromeric Kv1.1/1.2 current by Amyloid Beta (1‐42) Peptide: Implications for Alzheimer’s Disease
Alzheimer s & Dementia · 2024
- Rapid suppression of macroscopic homomeric Kv1.2 and heteromeric Kv1.1/1.2 currents by amyloid beta (1‐42) peptide: Implications for Alzheimer’s disease
Alzheimer s & Dementia · 2023
- Amyloid beta (1‐42) peptide suppression of macroscopic homomeric Kv1.2 and heteromeric Kv1.1/1.2 currents is calcium‐ and calcineurin‐dependent: Implications for Alzheimer’s disease
Alzheimer s & Dementia · 2023
- Suppression of Kv1.1 Channel Activity by Beta-Amyloid Peptides Involves both Intracellular Calcium-Signaling and Direct Peptide-Peptide Interactions
Biophysical Journal · 2021
- Signaling Mechanisms Underlying Nicotine-Induced Upregulation of α7 Nicotinic Acetylcholine Receptor (nAChR)
Biophysical Journal · 2020
- Suppressive Effects of Beta Amyloid Peptides (1-42) and (25-35) on Kv1.1 Channel Activity
Biophysical Journal · 2019
- P1‐162: SUPPRESSIVE EFFECTS OF AMYLOID PEPTIDE FRAGMENTS ON MACRO‐ AND MICRO‐SCOPIC KV1.1 CHANNEL ACTIVITY
Alzheimer s & Dementia · 2019
- P1‐169: ALLOSTERIC REGULATION OF α7 NACHRS BY LOW AND HIGH Aβ(1‐42) CONCENTRATIONS
Alzheimer s & Dementia · 2019
- Endocytosis Participation in Nicotine-Induced Upregulation of Alpha 7 (A7) Nicotinic Acetylcholine Receptors (nAChRs) in Xenopus Oocytes
Biophysical Journal · 2018
- P1‐193: SUPPRESSION OF KV1.1 CHANNEL ACTIVITY BY AMYLOID PEPTIDE FRAGMENTS (1‐42) AND THE TOXIC CORE (25‐35)
Alzheimer s & Dementia · 2018
- P1‐176: FACILITATION EFFECTS OF SUB‐NANOMOLAR CONCENTRATIONS OF Aβ(1‐42) ON α7 NACHRS IN <i>XENOPUS</i> OOCYTES
Alzheimer s & Dementia · 2018
- Mechanisms of Kv1.1 Channel Activity Suppression by Beta Amyloid 42
Biophysical Journal · 2017
- Nicotine-Upregulation of Alpha 7 nAChR in Xenopus Oocytes
Biophysical Journal · 2016
- Alzheimer s & Dementia×8
- Biophysical Journal×7
This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.
Last updated Jul 11, 2026.
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