Publications
153
Citations
743
Est. group size
~19
Recurring co-author estimate
Active years
22
Publishing since 2005
Kevin M. Huang studies how drug transporter proteins (molecular 'gatekeepers' that move drugs into and out of cells) influence the side effects of cancer chemotherapy, including heart toxicity, nerve damage, and gastrointestinal problems. This work often uses mouse models and cell-based assays to identify which transporters (such as OCT3, OATP1B1, OATP2B1, and P-glycoprotein) control drug movement into specific tissues, with the goal of predicting or preventing drug-induced toxicity. The research sits at the intersection of pharmacology and cancer treatment, focusing on why some chemotherapy and targeted cancer drugs harm healthy organs.
Publication output was relatively steady and modest from 2017–2022 but has grown sharply since 2023, reaching its highest levels in 2024–2025.
Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026
- Role of solute carrier transporters in the biodistribution and toxicity of chemotherapeutic drugs
Pharmacological Reviews · 2026
- Insights and perspectives into the etiology of TKI-induced cardiotoxicity
ASPET Discovery · 2026
- Transporter-Dependent Mechanism of Drug-Induced Cardiotoxicity (Abstract ID: 234600)
Journal of Pharmacology and Experimental Therapeutics · 2026
- A Cardiac-Specific Humanized Mouse Model to Evaluate the Disposition of OCT3 Substrates (Abstract ID: 232616)
Journal of Pharmacology and Experimental Therapeutics · 2026
- The Novel OCT3 Inhibitor Peficitinib Attenuates Doxorubicin-Induced Cardiotoxicity (Abstract ID: 227652)
Journal of Pharmacology and Experimental Therapeutics · 2026
- Interaction of Neuropathic Tubulin Poison Payloads with OATP1B-type Transporters (Abstract ID: 160927)
Journal of Pharmacology and Experimental Therapeutics · 2025
- <scp>OATP2B1</scp> Deficiency Ameliorates Irinotecan‐Induced Gastrointestinal Toxicity
Clinical and Translational Science · 2025
- Identification of OCT3 Inhibitors for Preventing Cardiac Accumulation of Toxic Substrates (Abstract ID: 165096)
Journal of Pharmacology and Experimental Therapeutics · 2025
- P-glycoprotein (P-gp) Deficiency Exacerbates Vincristine-Induced Peripheral Neuropathy (Abstract ID: 162685)
Journal of Pharmacology and Experimental Therapeutics · 2025
- Identification of pazopanib as an OATP1B1 substrate by competitive counterflow screeen
Drug Metabolism and Pharmacokinetics · 2025
- Drug–drug interactions in targeted cancer therapies: a focus on tyrosine kinase inhibitors
Expert Review of Clinical Pharmacology · 2025
- Meta-Iodobenzylguanidine as an Exogenous Biomarker of Cardiac OCT3 Function
Journal of Pharmacology and Experimental Therapeutics · 2024
- Figure S5 from Regulation of OATP1B1 Function by Tyrosine Kinase–mediated Phosphorylation
2023
- Figure S4 from Regulation of OATP1B1 Function by Tyrosine Kinase–mediated Phosphorylation
2023
- Figure S3 from Regulation of OATP1B1 Function by Tyrosine Kinase–mediated Phosphorylation
2023
- Journal of Pharmacology and Experimental Therapeutics×7
- The FASEB Journal×6
- Cancer Research Communications×3
- Clinical Cancer Research×2
- Journal of Clinical Investigation×2
- Anika T. Chowdhury
Medicine · The Ohio State University
- Mahesh R. Nepal
Medicine · The Ohio State University
- Josie A. Silvaroli
Medicine · The Ohio State University
- Zahra Talebi
Medicine · The Ohio State University
- Navjotsingh Pabla
Medicine · The Ohio State University
This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.
Last updated Jul 19, 2026.
Claim or correct this profile