Kenneth J. Oestreich
Immunology and Microbiology · The Ohio State University
Publications
96
Citations
4,268
Est. group size
~15
Recurring co-author estimate
Active years
21
Publishing since 2006
Kenneth J. Oestreich's research focuses on how immune cells, particularly CD4+ T helper cells, decide which specialized role to take on during an immune response—for example becoming follicular helper T cells (which help antibody-producing B cells) versus other T helper subtypes. The work looks at the molecular switches (transcription factors like Bcl6, Blimp1, T-bet, IRF4, and STAT proteins) that control these cell-fate decisions, with relevance to vaccine responses, autoimmune disease, and cancer immunotherapy.
Publication output has fluctuated over the last decade with a peak in 2022, followed by a decline through 2024-2025 and a slight uptick projected for 2026, averaging about 6-7 publications per year over the last five years.
Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026
- A new ‘K’ind of T helper cell
Nature Immunology · 2026
- Faculty Opinions recommendation of Dependence on Bcl6 and Blimp1 drive distinct differentiation of murine memory and follicular helper CD4+ T cells.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · 2022
- Faculty Opinions recommendation of Gain-of-function IKZF1 variants in humans cause immune dysregulation associated with abnormal T/B cell late differentiation.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · 2022
- Faculty Opinions recommendation of Immune tolerance of food is mediated by layers of CD4+ T cell dysfunction.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · 2022
- Faculty Opinions recommendation of Early T-bet promotes LFA1 upregulation required for CD8+ effector and memory T cell development.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · 2022
- Vasculogenic Pericytes Directly Couple to the Emerging Endothelium During Vessel Formation
SSRN Electronic Journal · 2021
- Faculty Opinions recommendation of Selenium-GPX4 axis protects follicular helper T cells from ferroptosis.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · 2021
- Pericytes Directly Communicate with Emerging Endothelial Cells During Vasculogenesis
bioRxiv (Cold Spring Harbor Laboratory) · 2020
- IkZF and STAT factor regulatory modules as drivers of TH1 and TFH cell differentiation decisions
The Journal of Immunology · 2020
- High-frequency irreversible electroporation is an effective tumor ablation strategy that induces immunologic cell death and promotes systemic anti-tumor immunity
EBioMedicine · 2019
- Inhibition of IL-2 responsiveness by IL-6 is required for the generation of GC-T <sub>FH</sub> cells
Science Immunology · 2019
- Utilization of High-Frequency Irreversible Electroporation (H-FIRE) to modulate the tumor microenvironment and promote systemic immune system activation in breast cancer
The Journal of Immunology · 2018
- Additional file 1: Figure S1-S4. of Control of lupus nephritis by changes of gut microbiota
Figshare · 2017
- Additional file 1: Figure S1-S4. of Control of lupus nephritis by changes of gut microbiota
Figshare · 2017
- TIPS pentacene loaded PEO-PDLLA core-shell nanoparticles have similar cellular uptake dynamics in M1 and M2 macrophages and in corresponding in vivo microenvironments
Nanomedicine Nanotechnology Biology and Medicine · 2016
- The Journal of Immunology×27
- Figshare×6
- bioRxiv (Cold Spring Harbor Laboratory)×5
- Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature×5
- Frontiers in Immunology×3
- Kaitlin A. Read
Immunology and Microbiology · The Ohio State University
- Randy R. Brutkiewicz
Immunology and Microbiology · Indiana University
- Jasmine A. Tuazon
Immunology and Microbiology · The Ohio State University
- Jianhua Yu
Immunology and Microbiology · The Ohio State University
- Richard Dutton
Immunology and Microbiology · The Ohio State University
This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.
Last updated Jul 19, 2026.
Claim or correct this profile