Kedryn K. Baskin

Kedryn K. Baskin studies how the heart and other metabolic tissues (like skeletal muscle, liver, kidney, and fat) regulate their function through gene expression and metabolism, with particular focus on a gene-regulatory complex called Mediator (including subunits MED12 and MED13) and its role in heart muscle contraction and calcium signaling. The lab also examines how diet (such as high-phosphate or high-fat diets) and exercise affect mitochondrial function, fatty acid metabolism, and exercise capacity, connecting nutrition and physical activity to heart and metabolic disease. This work combines mouse models, gene editing tools like CRISPR, and molecular biology to understand cardiac and metabolic disease mechanisms.

Publication output has grown substantially over the last decade, rising from just 1-3 papers per year in 2017-2021 to 6-11 per year in 2022-2025.

Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026