Kedric L. Milholland
Biochemistry, Genetics and Molecular Biology · Purdue University West Lafayette
Publications
15
Citations
55
Est. group size
~6
Recurring co-author estimate
Active years
9
Publishing since 2018
Kedric L. Milholland's research focuses on Cdc14 phosphatases, a family of enzymes that remove phosphate groups from proteins to regulate cell division and other cellular processes, studied across organisms including yeast, the ciliated protozoan Tetrahymena, fungal pathogens like Candida, and humans. The work combines structural and mechanistic biochemistry with the development of chemical tools, including new enzyme inhibitors and genetic techniques for controlling protein levels in cells. This research could interest students curious about molecular mechanisms of cell division, enzyme regulation, drug discovery targeting phosphatases, or antifungal research strategies.
Publication output was low and sporadic from 2017-2021 but increased noticeably from 2022-2023, followed by a slight decline through 2025-2026.
Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026
- Expansion and optimization of the auxin-inducible degron 2 (AID2) system in <i>Candida</i> pathogens
bioRxiv (Cold Spring Harbor Laboratory) · 2026
- Abstract 2208 Characterization of an expanded Cdc14 phosphatase family in the ciliated protozoan Tetrahymena thermophila
Journal of Biological Chemistry · 2025
- Cdc14 phosphatases use an intramolecular pseudosubstrate motif to stimulate and regulate catalysis
Journal of Biological Chemistry · 2024
- Development of Novel Phosphonodifluoromethyl-Containing Phosphotyrosine Mimetics and a First-In-Class, Potent, Selective, and Bioavailable Inhibitor of Human CDC14 Phosphatases
Journal of Medicinal Chemistry · 2024
- Abstract 2160: Human Cdc14 Phosphatase Stimulation by a
Journal of Biological Chemistry · 2023
- Localization of Cdc14 Isoforms to Ciliary Structures in <i>Tetrahymena thermophila</i>
The FASEB Journal · 2022
- Identification of a Pseudosubstrate Stimulatory Motif Uncovers Novel Roles of Cdc14 Phosphatase in Fungal Cell Wall Integrity
The FASEB Journal · 2022
- Human Cdc14 Phosphatase Stimulation by an Intramolecular Pseudosubstrate Motif
The FASEB Journal · 2022
- Correction to: Genetically encoded photochemical covalent crosslinking within the Hcp-1 self-assembling bacterial secretion machinery
Amino Acids · 2019
- Genetically encoded photochemical covalent crosslinking within the Hcp-1 self-assembling bacterial secretion machinery
Amino Acids · 2018
- Journal of Biological Chemistry×3
- bioRxiv (Cold Spring Harbor Laboratory)×3
- The FASEB Journal×3
- Amino Acids×2
- Scientific Reports×1
- Andrew G. DeMarco
Biochemistry, Genetics and Molecular Biology · Purdue University West Lafayette
- Jian‐Qiu Wu
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- Lea Schroeder
Biochemistry, Genetics and Molecular Biology · Purdue University West Lafayette
- Aysha H. Osmani
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- Stephen A. Osmani
Biochemistry, Genetics and Molecular Biology · The Ohio State University
This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.
Last updated Jul 20, 2026.
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