Katherine J. Ladner
Biochemistry, Genetics and Molecular Biology · The Ohio State University
Publications
50
Citations
4,913
Est. group size
—
Recurring co-author estimate
Active years
34
Publishing since 1992
Katherine J. Ladner's work centers on cancer biology and experimental cancer therapies, including CRISPR-engineered immune cells for treating metastatic colorectal cancer, Tumor Treating Fields (TTFields) as a physical therapy for cancers like mesothelioma and glioblastoma, and how cancer cells communicate via structures called tunneling nanotubes. Her research combines lab experiments, deep learning image analysis, and early-phase clinical trials to study tumor behavior and evaluate new treatment approaches. This work is relevant to students interested in cancer immunotherapy, biophysical cancer cell analysis, and translational oncology research.
Publication output was low and sporadic from 2017–2021 but increased notably from 2022 onward, suggesting growing recent research activity.
Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026
- Targeting the intracellular immune checkpoint CISH with CRISPR-Cas9-edited T cells in patients with metastatic colorectal cancer: a first-in-human, single-centre, phase 1 trial
The Lancet Oncology · 2025
- SARS-CoV-2 infection drives local inflammation of the intestinal epithelium in immunocompromised patients with cancer
iScience · 2025
- Protocol for applying Tumor Treating Fields in mouse models of cancer using the inovivo system
STAR Protocols · 2025
- Abstract CT269: First-in-human trial in patients with metastatic colorectal cancer using CRISPR-engineered tumor infiltrating lymphocytes in which the intracellular immune checkpoint <i>CISH</i> is inhibited
Cancer Research · 2025
- Treatment with tumor-treating fields (TTFields) suppresses intercellular tunneling nanotube formation in vitro and upregulates immuno-oncologic biomarkers in vivo in malignant mesothelioma
eLife · 2023
- Data from IFN-α and Bortezomib Overcome Bcl-2 and Mcl-1 Overexpression in Melanoma Cells by Stimulating the Extrinsic Pathway of Apoptosis
2023
- Supplementary Figure Legends from IFN-α and Bortezomib Overcome Bcl-2 and Mcl-1 Overexpression in Melanoma Cells by Stimulating the Extrinsic Pathway of Apoptosis
2023
- Supplementary Figures 1-8 from IFN-α and Bortezomib Overcome Bcl-2 and Mcl-1 Overexpression in Melanoma Cells by Stimulating the Extrinsic Pathway of Apoptosis
2023
- Supplementary Figures 1-8 from IFN-α and Bortezomib Overcome Bcl-2 and Mcl-1 Overexpression in Melanoma Cells by Stimulating the Extrinsic Pathway of Apoptosis
2023
- Supplementary Figure Legends from IFN-α and Bortezomib Overcome Bcl-2 and Mcl-1 Overexpression in Melanoma Cells by Stimulating the Extrinsic Pathway of Apoptosis
2023
- Author response: Treatment with tumor-treating fields (TTFields) suppresses intercellular tunneling nanotube formation in vitro and upregulates immuno-oncologic biomarkers in vivo in malignant mesothelioma
2023
- Data from IFN-α and Bortezomib Overcome Bcl-2 and Mcl-1 Overexpression in Melanoma Cells by Stimulating the Extrinsic Pathway of Apoptosis
2023
- Molecular alterations associated with improved outcome in patients with glioblastoma treated with Tumor-Treating Fields
Neuro-Oncology Advances · 2022
- Tunneling Nanotubes between Cells Migrating in ECM Mimicking Fibrous Environments
Cancers · 2022
- TNTdetect.AI: A Deep Learning Model for Automated Detection and Counting of Tunneling Nanotubes in Microscopy Images
Cancers · 2022
- Cancer Research×4
- Cell Reports×2
- Cancers×2
- bioRxiv (Cold Spring Harbor Laboratory)×2
- Journal of Clinical Investigation×1
- Ashok Kumar
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- Fabrizio Pin
Biochemistry, Genetics and Molecular Biology · Indiana University
- Jason D. Doles
Biochemistry, Genetics and Molecular Biology · Indiana University
- Thomas A. Kwiatkowski
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- Joshua R. Huot
Biochemistry, Genetics and Molecular Biology · Indiana University
This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.
Last updated Jul 19, 2026.
Claim or correct this profile