Karl Obrietan
Neuroscience · The Ohio State University
Publications
125
Citations
12,200
Est. group size
~2
Recurring co-author estimate
Active years
32
Publishing since 1995
Karl Obrietan studies the brain's circadian clock, focusing on the suprachiasmatic nucleus (SCN), the brain region that generates daily rhythms in behavior and physiology. Recent work examines how this clock is disrupted in neurodegenerative conditions like Alzheimer's disease models (amyloid-beta and tau pathology), as well as molecular signaling pathways (such as microRNAs and kinases) involved in memory, stress responses, and neuronal survival. The lab also has projects on drug pharmacokinetics and neonatal opioid withdrawal models.
Publication output has fluctuated over the last decade, dipping around 2022-2023 before rebounding to a steadier pace of about 5 papers per year in 2024-2025.
Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026
- Cellular- and systems-level profiling of amyloid-beta effects on circadian timing
Neurobiology of Disease · 2026
- Circadian timing and entrainment properties of the SCN pacemaker in the PS19 mouse model of tau pathology
Experimental Neurology · 2025
- Circadian timing and entrainment properties of the SCN pacemaker in the PS19 mouse model of tau pathology
bioRxiv (Cold Spring Harbor Laboratory) · 2025
- Cellular- and systems-level profiling of amyloid-beta effects on circadian timing
bioRxiv (Cold Spring Harbor Laboratory) · 2025
- Ribosomal S6 kinase signaling regulates neuronal viability during development and confers resistance to excitotoxic cell death in mature neurons
Neuroscience · 2024
- Strain- and Route-Dependent Plasma Pharmacokinetics and DRG Accumulation of Paclitaxel
Journal of Pharmacology and Experimental Therapeutics · 2024
- Characterizing Imatinib’s Pharmacokinetics and Impact on Neuronal p-ERK Signaling
Journal of Pharmacology and Experimental Therapeutics · 2024
- Review for "Behavioural phenotypes of <i>Dicer</i> knockout in the mouse SCN"
2024
- Circadian clocks, cognition, and Alzheimer’s disease: synaptic mechanisms, signaling effectors, and chronotherapeutics
Molecular Neurodegeneration · 2022
- MicroRNA-212-5p, an anti-proliferative miRNA, attenuates hypoxia and sugen/hypoxia-induced pulmonary hypertension in rodents
Molecular Therapy — Nucleic Acids · 2022
- Pharmacological Prevention of Neonatal Opioid Withdrawal in a Pregnant Guinea Pig Model
Frontiers in Pharmacology · 2021
- Pharmacological prevention of neonatal opioid withdrawal in a pregnant guinea pig model
bioRxiv (Cold Spring Harbor Laboratory) · 2020
- Author response for "SynGAP is expressed in the murine suprachiasmatic nucleus and regulates circadian‐gated locomotor activity and light‐entrainment capacity"
2020
- Author response for "SynGAP is expressed in the murine suprachiasmatic nucleus and regulates circadian‐gated locomotor activity and light‐entrainment capacity"
2020
- A Symphony of Signals: Intercellular and Intracellular Signaling Mechanisms Underlying Circadian Timekeeping in Mice and Flies
International Journal of Molecular Sciences · 2019
- Brain Behavior and Immunity×3
- Neuroscience×3
- bioRxiv (Cold Spring Harbor Laboratory)×3
- European Journal of Neuroscience×2
- Learning & Memory×2
- Ruifeng Cao
Neuroscience · The Ohio State University
- Aishwarya Ramakrishnan
Neuroscience · Indiana University
- Tracy A. Bedrosian
Neuroscience · The Ohio State University
- Sudhanshu Shekhar
Neuroscience · Purdue University West Lafayette
- Kari R. Hoyt
Neuroscience · The Ohio State University
This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.
Last updated Jul 19, 2026.
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