Karen T. Liby
Biochemistry, Genetics and Molecular Biology · Indiana University
Publications
265
Citations
10,404
Est. group size
—
Recurring co-author estimate
Active years
27
Publishing since 1999
Karen T. Liby studies how specially designed small molecules can prevent or treat cancer, focusing on synthetic compounds such as triterpenoids and retinoid X receptor (RXR) agonists. Her work examines how these agents shape the tumor's surrounding immune environment and influence signaling pathways like NRF2/KEAP1, often using mouse models of lung, breast, skin, and NF1-associated cancers. A key theme is chemoprevention—stopping cancer before it fully develops—and combining these compounds with existing therapies.
Publication activity has been steady across most years with a sharp one-year spike in 2023, and recent output remains active at roughly 10 papers per year.
Generated by claude-opus-4-8 from public bibliographic data · Jul 9, 2026
Typically publishes in teams of ~6 · 14% small-team papers (≤3 authors) · across 44 venues
- Synthetic Oleanane Triterpenoids Reduce Tumor Growth and Promote an Anti-Tumor Immune Response Independent of Cancer KEAP1 Mutational Status
Antioxidants · 2025
- Understanding how treatment responses alter the myeloid compartment in BRAF-mutant melanoma 2604
The Journal of Immunology · 2025
- 1002 A novel RXR agonist suppresses tumor formation accompanied by increased CD8+ T cells in a murine model of cutaneous T cell lymphoma (CTCL)
Journal of Investigative Dermatology · 2025
- The RXR Agonist MSU-42011 Reduces Tumor Burden in a Murine Preclinical NF1-Deficient Model
Cancers · 2025
- Abstract 3450: The role of NRF2-HO-1 expressing macrophages in lung cancer progression
Cancer Research · 2025
- Abstract 3096: The RXR agonist MSU-42011 and the MEK inhibitor selumetinib reduce tumor burden by decreasing pERK levels and modulating immune cell populations within the NF1 tumor microenvironment
Cancer Research · 2025
- Abstract 3130: Differential gene expression regulation by the RXR agonist V-125 in MMTV-Neu mammary tumors
Cancer Research · 2025
- Abstract 3165: Leveraging chemoinformatics and high-throughput screening for the identification of novel ubiquitin specific protease 7 (USP7) inhibitors
Cancer Research · 2025
- RXR Agonist V-125 Induces Distinct Transcriptional and Immunomodulatory Programs in Mammary Tumors of MMTV-Neu Mice Compared to Bexarotene
Biomedicines · 2025
- Health position paper and redox perspectives – Bench to bedside transition for pharmacological regulation of NRF2 in noncommunicable diseases
Redox Biology · 2025
- P07-21 Chloropicrin induces transcriptional changes in mouse cornea
Toxicology Letters · 2024
- Mechanistic and Clinical Chemoprevention
Elsevier eBooks · 2024
- Abstract 2021: The RXR agonist MSU-42011 and the MEK inhibitor selumetinib reduce pERK levels in NF1-deficient cells and inhibit cytokine production in macrophages
Cancer Research · 2024
- Abstract 2642: KEAP1 mutation in lung cancer cells leads to increased immunosuppressive capability
Cancer Research · 2024
- Abstract 761: The relationship between ANGPTL4 and epidermal malignant transformation
Cancer Research · 2024
- Cancer Research×31
- Scientific Reports×7
- The Journal of Immunology×5
- Cancer Prevention Research×3
- Cancers×3
- Steffen M. Bernard
Biochemistry, Genetics and Molecular Biology · University of Michigan
- Emily Ho
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- Ajeet Kumar Verma
Biochemistry, Genetics and Molecular Biology · The Ohio State University
- Anita A. Panjwani
Biochemistry, Genetics and Molecular Biology · Purdue University West Lafayette
- Davinder Singh
Biochemistry, Genetics and Molecular Biology · The Ohio State University
This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.
Last updated Sep 1, 2026.
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