Karen Bush
Biochemistry, Genetics and Molecular Biology · Indiana University
Publications
308
Citations
31,225
Est. group size
—
Recurring co-author estimate
Active years
60
Publishing since 1966
Karen Bush studies how bacteria resist antibiotics, with a particular focus on β-lactamases—enzymes that bacteria produce to break down common antibiotics like penicillins and carbapenems. The research covers how these enzymes are classified and named, how they spread, and how new drug combinations (such as antibiotics paired with β-lactamase inhibitors) can overcome resistant infections. Much of the work reviews and evaluates antibacterial agents in clinical development.
Publication activity has slowed over the last decade, dropping from around nine papers per year in 2017 to roughly two to four in recent years.
Generated by claude-opus-4-8 from public bibliographic data · Jul 9, 2026
Typically publishes in teams of ~2 · 56% small-team papers (≤3 authors) · across 18 venues
- Past, present, and future perspectives on aztreonam and avibactam
Expert Review of Anti-infective Therapy · 2025
- SAND: a comprehensive annotation of class D β-lactamases using structural alignment-based numbering
Antimicrobial Agents and Chemotherapy · 2025
- Commentary on The antibiotic explosion by H. Boyd Woodruff and Richard W. Burg
Elsevier eBooks · 2024
- Contributors
Elsevier eBooks · 2024
- AB0477 EXPERIENCES AND PERSPECTIVES OF PATIENTS WITH PSORIATIC ARTHRITIS PARTICIPATING IN A RANDOMIZED CONTROLLED TRIAL OF DIETARY INTERVENTIONS
Annals of the Rheumatic Diseases · 2024
- Classification for β-lactamases: historical perspectives
Expert Review of Anti-infective Therapy · 2023
- AB1122 GUSELKUMAB VS GOLIMUMAB IN PSA TNFI-INADEQUATE RESPONDERS (EVOLUTION): FORMULATING A PRAGMATIC PHASE 3B RANDOMIZED TRIAL
Annals of the Rheumatic Diseases · 2023
- Antibacterial Agents
ClinMicroNow · 2023
- Antibacterial Agents
ClinMicroNow · 2023
- Consensus on β-Lactamase Nomenclature
Antimicrobial Agents and Chemotherapy · 2022
- In vitro antibacterial activity of cefiderocol against recent multidrug-resistant carbapenem-nonsusceptible Enterobacterales isolates
Diagnostic Microbiology and Infectious Disease · 2022
- A Tribute to George A. Jacoby
Antimicrobial Agents and Chemotherapy · 2022
- Success and Challenges Associated with Large-Scale Collaborative Surveillance for Carbapenemase Genes in Gram-Negative Bacteria
Antimicrobial Agents and Chemotherapy · 2021
- Epidemiology of β-Lactamase-Producing Pathogens
Clinical Microbiology Reviews · 2020
- Critical analysis of antibacterial agents in clinical development
Nature Reviews Microbiology · 2020
- Antimicrobial Agents and Chemotherapy×9
- Nature Reviews Microbiology×4
- Journal of Antimicrobial Chemotherapy×4
- Elsevier eBooks×3
- Expert Review of Anti-infective Therapy×2
- Samuel L Aitken
Biochemistry, Genetics and Molecular Biology · University of Michigan
- Jason M. Pogue
Biochemistry, Genetics and Molecular Biology · University of Michigan
- Keith S. Kaye
Biochemistry, Genetics and Molecular Biology · University of Michigan
- Walaiporn Wangchinda
Biochemistry, Genetics and Molecular Biology · University of Michigan
- Paul Lephart
Biochemistry, Genetics and Molecular Biology · University of Michigan
This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.
Last updated Sep 1, 2026.
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