Jude C. Kluemper

Medicine · The Ohio State University

Early career · publishing since 2017Rising activity

Reconstructive Surgery and Microvascular Techniques Adipose Tissue and Metabolism Traumatic Brain Injury and Neurovascular Disturbances Lipid metabolism and biosynthesis Metabolomics and Mass Spectrometry Studies

Publications

Citations

536

Est. group size

Recurring co-author estimate

Active years

Publishing since 2017

Research summary

AI-generated

This researcher studies how a gene variant called APOE4, which is a known risk factor for Alzheimer's disease, affects brain cell metabolism, including how brain support cells (astrocytes) process fats and sugars for energy. Their work also touches on lipid droplets (fat storage structures within cells) and their role in neurodegenerative diseases. This research aims to understand the biological mechanisms that link genetics, cell metabolism, and brain disease risk.

APOE4 and Alzheimer's disease riskBrain cell energy metabolismLipid droplets and fat storage in cellsAstrocyte biologyNeurodegeneration mechanisms

Publication output was low and irregular from 2017 through 2023 (0-2 papers per year) but has increased notably since 2024, with a sharp rise in 2025.

Generated by claude-sonnet-5 from public bibliographic data · Jul 20, 2026

Publication cadence

Publications per year over the last 10 years — averaging 3.2/year recently

Recent publications

APOΕ4 lowers energy expenditure in females and impairs glucose oxidation by increasing flux through aerobic glycolysis
Molecular Neurodegeneration · 2021
Additional file 1 of APOΕ4 lowers energy expenditure in females and impairs glucose oxidation by increasing flux through aerobic glycolysis
Open MIND · 2021
Lipid Droplets in Neurodegenerative Disorders
Frontiers in Neuroscience · 2020
APOE4 Lowers Energy Expenditure and Impairs Glucose Oxidation by Increasing Flux through Aerobic Glycolysis
bioRxiv (Cold Spring Harbor Laboratory) · 2020
Apolipoprotein E4 Alters Astrocyte Fatty Acid Metabolism and Lipid Droplet Formation
Cells · 2019
P1‐192: APOLIPOPROTEIN E4 PROMOTES LIPID DROPLET ACCUMULATION IN ASTROCYTES
Alzheimer s & Dementia · 2019
Dynamics of peroxisomes - from protein to organelle level
European Biophysics Journal · 2017

Publishes in

Plastic & Reconstructive Surgery Global Open×11
Frontiers in Neuroscience×1
Cells×1
Molecular Neurodegeneration×1
Arthroplasty Today×1

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This profile was generated automatically from public scholarly data (OpenAlex). Group size and activity levels are estimates derived from co-authorship patterns.

Last updated Jul 19, 2026.

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